Bacterial superantigens (SAgs) are effective T-cell stimulatory molecules that lead to
massive cytokine production. Superantigens crosslink between MHC class II molecules on …

Bacterial superantigens are T-cell-stimulatory protein molecules which produce massive
cytokines and cause human diseases. Due to their ability to activate up to 20% of resting T …

Hepatocellular carcinoma (HCC), one of the most common and malignant tumors worldwide,
is unresponsive to any of the available therapies. Using intact HCC cells as therapeutic …

Tumor-targeted superantigens (TTSs) have been used to treat a variety of tumors in
preclinical studies. The TTS utilizes the powerful T-cell activation strategy by means of …

Superantigens (SAgs) are a collection of bacterial and viral proteins with potent
immunostimulatory properties. SAgs bind to Major Histocompatibility Complex Class II (MHC …

Background Monoclonal antibodies have been employed as targeting molecules of
superantigen for the preclinical treatment of a variety of tumours. However, other targeting …

OBJECTIVE: Bacterial superantigens (SAgs) are proteins produced by few types of bacteria
that have been linked to several human diseases. Due to their potent in vitro and in vivo …

Recent research has attempted to direct superantigens towards tumors by means of tumor-
targeted superantigen (TTS) strategy. In this study, we explored the antitumor property of …

Superantigens (SAgs) are a class of antigens that cause non-specific activation of T-cells
resulting in polyclonal T cell activation and massive cytokine release and causing symptoms …

Superantigens (SAg) are a family of bacterial and viral proteins with strong
immunostimulatory properties. SAg bound to major histocompatibility complex (MHC) class II …