Metabolic adaptations of Pseudomonas aeruginosa during cystic fibrosis chronic lung infections
V Behrends, B Ryall, JEA Zlosnik… - Environmental …, 2013 - Wiley Online Library
Pseudomonas aeruginosa forms chronic infections in the lungs of cystic fibrosis (CF)
patients, and is the leading cause of morbidity and mortality in patients with CF …
patients, and is the leading cause of morbidity and mortality in patients with CF …
Pseudomonas aeruginosa syntrophy in chronically colonized airways of cystic fibrosis patients
X Qin, DM Zerr, MA McNutt, JE Berry… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Pseudomonas aeruginosa isolates from cystic fibrosis (CF) patients undergo remarkable
phenotypic divergence over time, including loss of pigmentation, hemolysis, motility, and …
phenotypic divergence over time, including loss of pigmentation, hemolysis, motility, and …
Pseudomonas aeruginosa Microevolution during Cystic Fibrosis Lung Infection Establishes Clones with Adapted Virulence
A Bragonzi, M Paroni, A Nonis, N Cramer… - American journal of …, 2009 - atsjournals.org
Rationale: During long-term lung infection in patients with cystic fibrosis (CF), Pseudomonas
aeruginosa strains develop mutations leading to clonal expansion. This microevolution is …
aeruginosa strains develop mutations leading to clonal expansion. This microevolution is …
[HTML][HTML] Molecular detection of an atypical, highly resistant, clonal Pseudomonas aeruginosa isolate in cystic fibrosis patients
D Keating, MJ Crowe, B Kennedy, A Salmon… - Journal of Cystic …, 2013 - Elsevier
BACKGROUND: The identification of Pseudomonas aeruginosa (P. aeruginosa) isolates in
sputum from cystic fibrosis (CF) patients can be challenging due to the multitude of …
sputum from cystic fibrosis (CF) patients can be challenging due to the multitude of …
Dynamics of Adaptive Microevolution of Hypermutable Pseudomonas aeruginosa during Chronic Pulmonary Infection in Patients with Cystic Fibrosis
C Hoboth, R Hoffmann, A Eichner… - The Journal of …, 2009 - academic.oup.com
Background. In patients with cystic fibrosis (CF), the emergence of hypermutable
Pseudomonas aeruginosa drives the selection of P. aeruginosa variants that are efficiently …
Pseudomonas aeruginosa drives the selection of P. aeruginosa variants that are efficiently …
Genomic variation among contemporary Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients
JCS Chung, J Becq, L Fraser… - Journal of …, 2012 - Am Soc Microbiol
The airways of individuals with cystic fibrosis (CF) often become chronically infected with
unique strains of the opportunistic pathogen Pseudomonas aeruginosa. Several lines of …
unique strains of the opportunistic pathogen Pseudomonas aeruginosa. Several lines of …
Selective sweeps and parallel pathoadaptation drive Pseudomonas aeruginosa evolution in the cystic fibrosis lung
J Diaz Caballero, ST Clark, B Coburn, Y Zhang… - MBio, 2015 - Am Soc Microbiol
Pulmonary infections caused by Pseudomonas aeruginosa are a recalcitrant problem in
cystic fibrosis (CF) patients. While the clinical implications and long-term evolutionary …
cystic fibrosis (CF) patients. While the clinical implications and long-term evolutionary …
[HTML][HTML] Within-host microevolution of Pseudomonas aeruginosa in Italian cystic fibrosis patients
Abstract Background Chronic infection with Pseudomonas aeruginosa is a major cause of
morbidity and mortality in cystic fibrosis (CF) patients, and a more complete understanding of …
morbidity and mortality in cystic fibrosis (CF) patients, and a more complete understanding of …
Evolutionary insight from Whole-Genome Sequencing of Pseudomonas Aeruginosa from Cystic Fibrosis Patients
The opportunistic pathogen Pseudomonas aeruginosa causes chronic airway infections in
patients with cystic fibrosis (CF), and it is directly associated with the morbidity and mortality …
patients with cystic fibrosis (CF), and it is directly associated with the morbidity and mortality …
Adaptation of Pseudomonas aeruginosa to the cystic fibrosis airway: an evolutionary perspective
The airways of patients with cystic fibrosis (CF) are nearly always infected with many
different microorganisms. This environment offers warm, humid and nutrient-rich conditions …
different microorganisms. This environment offers warm, humid and nutrient-rich conditions …