Clonal epidemiology of Pseudomonas aeruginosa in cystic fibrosis

N Cramer, L Wiehlmann, B Tümmler - International Journal of Medical …, 2010 - Elsevier
The basic defect in cystic fibrosis (CF) predisposes to chronic bacterial airway infections,
particularly with Pseudomonas aeruginosa. Airway infections with P. aeruginosa in …

Unveiling the early events of Pseudomonas aeruginosa adaptation in cystic fibrosis airway environment using a long-term in vitro maintenance

AM Sousa, R Monteiro, MO Pereira - International Journal of Medical …, 2018 - Elsevier
Pseudomonas aeruginosa chronic infections are the major cause of high morbidity and
mortality in cystic fibrosis (CF) patients due to the use of sophisticated mechanisms of …

[HTML][HTML] Adaptation of Pseudomonas aeruginosa in Cystic Fibrosis Airways Influences Virulence of Staphylococcus aureus In Vitro and Murine Models of Co …

R Baldan, C Cigana, F Testa, I Bianconi, M De Simone… - PloS one, 2014 - journals.plos.org
Cystic fibrosis (CF) airways disease represents an example of polymicrobial infection
whereby different bacterial species can interact and influence each other. In CF patients …

Gene loss and acquisition in lineages of Pseudomonas aeruginosa evolving in cystic fibrosis patient airways

M Gabrielaite, HK Johansen, S Molin, FC Nielsen… - MBio, 2020 - Am Soc Microbiol
Genome analyses have documented that there are differences in gene repertoire between
evolutionary distant lineages of the same bacterial species; however, less is known about …

Pseudomonas aeruginosa Strain-sharing in Early Infection Among Children With Cystic Fibrosis

PJ Stapleton, C Izydorcyzk, S Clark… - Clinical Infectious …, 2021 - academic.oup.com
Abstract Background We previously identified Pseudomonas aeruginosa isolates with
characteristics typical of chronic infection in some early infections in children with cystic …

[HTML][HTML] Genetically and Phenotypically Distinct Pseudomonas aeruginosa Cystic Fibrosis Isolates Share a Core Proteomic Signature

A Penesyan, SS Kumar, K Kamath, AM Shathili… - PloS one, 2015 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa is among the main colonizers of the
lungs of cystic fibrosis (CF) patients. We have isolated and sequenced several P …

Diversity of metabolic profiles of cystic fibrosis Pseudomonas aeruginosa during the early stages of lung infection

KM Jørgensen, T Wassermann… - …, 2015 - microbiologyresearch.org
Pseudomonas aeruginosa is the dominant pathogen infecting the airways of cystic fibrosis
(CF) patients. During the intermittent colonization phase, P. aeruginosa resembles …

[HTML][HTML] From genotype to phenotype: adaptations of Pseudomonas aeruginosa to the cystic fibrosis environment

L Camus, F Vandenesch, K Moreau - Microbial genomics, 2021 - microbiologyresearch.org
Pseudomonas aeruginosa is one of the main microbial species colonizing the lungs of cystic
fibrosis patients and is responsible for the decline in respiratory function. Despite the hostile …

Polyclonality, Shared Strains, and Convergent Evolution in Chronic Cystic Fibrosis Staphylococcus aureus Airway Infection

DR Long, DJ Wolter, M Lee, M Precit… - American Journal of …, 2021 - atsjournals.org
Rationale: Staphylococcus aureus is the most common respiratory pathogen isolated from
patients with cystic fibrosis (CF) in the United States. Although modes of acquisition and …

Genome mosaicism is conserved but not unique in Pseudomonas aeruginosa isolates from the airways of young children with cystic fibrosis

RK Ernst, DA D′ Argenio, JK Ichikawa… - Environmental …, 2003 - Wiley Online Library
Pseudomonas aeruginosa strains from the chronic lung infections of cystic fibrosis (CF)
patients are phenotypically and genotypically diverse. Using strain PAO1 whole genome …