Genotypic and phenotypic relatedness of Pseudomonas aeruginosa isolates among the major cystic fibrosis patient cohort in Italy

C Cigana, P Melotti, R Baldan, E Pedretti, E Pintani… - BMC microbiology, 2016 - Springer
Background Pseudomonas aeruginosa is the predominant pathogen associated with the
decline of pulmonary function in cystic fibrosis (CF) patients. Both environment-to-host …

Co-occurring microflora and mucin drive Pseudomonas aeruginosa diversification and pathoadaptation

MJ Bottery, HK Johansen, JW Pitchford… - ISME …, 2024 - academic.oup.com
While several environmental factors contribute to the evolutionary diversification of the
pathogenic bacterium Pseudomonas aeruginosa during cystic fibrosis lung infections …

Turnover of strains and intraclonal variation amongst Pseudomonas aeruginosa isolates from paediatric CF patients

AJ Hall, JL Fothergill, PS McNamara… - … and infectious disease, 2014 - Elsevier
Transmissible strains of Pseudomonas aeruginosa in cystic fibrosis (CF) have been well
documented. Our longitudinal survey of P. aeruginosa isolates from 45 paediatric CF …

Molecular Epidemiology of Chronic Pseudomonas aeruginosa Airway Infections in Cystic Fibrosis

N Cramer, L Wiehlmann, O Ciofu, S Tamm, N Høiby… - PloS one, 2012 - journals.plos.org
Background/Methods The molecular epidemiology of the chronic airway infections with
Pseudomonas aeruginosa in individuals with cystic fibrosis (CF) was investigated by cross …

[HTML][HTML] Pseudomonas aeruginosa genotypes acquired by children with cystic fibrosis by age 5-years

TJ Kidd, KA Ramsay, S Vidmar, JB Carlin, SC Bell… - Journal of Cystic …, 2015 - Elsevier
Abstract Background We describe Pseudomonas aeruginosa acquisitions in children with
cystic fibrosis (CF) aged≤ 5-years, eradication treatment efficacy, and genotypic …

Positive Signature-Tagged Mutagenesis in Pseudomonas aeruginosa: Tracking Patho-Adaptive Mutations Promoting Airways Chronic Infection

I Bianconi, A Milani, C Cigana, M Paroni… - PLoS …, 2011 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa can establish life-long chronic
infections in the airways of cystic fibrosis (CF) patients. Persistent lifestyle is established with …

[HTML][HTML] Multilocus amplicon sequencing of Pseudomonas aeruginosa cystic fibrosis airways isolates collected prior to and after early antipseudomonal chemotherapy

S Fischer, L Greipel, J Klockgether, M Dorda… - Journal of Cystic …, 2017 - Elsevier
Background Early antimicrobial chemotherapy can prevent or at least delay chronic cystic
fibrosis (CF) airways infections with Pseudomonas aeruginosa. Methods During a 10-year …

Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa

JR Dettman, N Rodrigue, SD Aaron… - Proceedings of the …, 2013 - National Acad Sciences
Pseudomonas aeruginosa is an opportunistic pathogen of humans and is a major cause of
morbidity and mortality in patients with cystic fibrosis (CF). Prolonged infection of the …

Differential adaptation of microbial pathogens to airways of patients with cystic fibrosis and chronic obstructive pulmonary disease

G Döring, IG Parameswaran… - FEMS microbiology …, 2011 - academic.oup.com
Cystic fibrosis (CF), the most common autosomal recessive disorder in Caucasians, and
chronic obstructive pulmonary disease (COPD), a disease of adults, are characterized by …

Heterogeneous antimicrobial susceptibility characteristics in Pseudomonas aeruginosa isolates from cystic fibrosis patients

X Qin, C Zhou, DM Zerr, A Adler, A Addetia, S Yuan… - MSphere, 2018 - Am Soc Microbiol
Clinical isolates of Pseudomonas aeruginosa from patients with cystic fibrosis (CF) are
known to differ from those associated with non-CF hosts by colony morphology, drug …