Background: Anal fistula is an abnormal tract between the anal canal and the perianal skin.
Anal fistula plug (AFP) as a sphincter-preventing method has drawn more interest because …

Purpose The treatment of high transsphincteric fistula is a complex procedure, which may be
associated with the risk of recurrence and fecal incontinence. In this study, we used an …

Background: Using small intestinal submucosa (SIS) has increasingly become the standard
method for the treatment of anal fistula. The porcine SIS manufactured by Biosis Healing is a …

BACKGROUND: Bioprosthetic plugs represent a promising technique for the treatment of
anal fistula simple because they allow simple and repeatable application, preservation of …

Surgery for an anal fistula may result in recurrence or impairment of continence. The ideal
treatment for an anal fistula should be associated with low recurrence rates, minimal …

We report on a clinicopathologic study in an animal model of treatment with a new
bioabsorbable polymer plug (BAPP). Over a 2-week period, 6 porcine models, which each …

Background The mostly widely studied biomaterials for the sphincter sparing treatment of
anal fistulas are fibrin glue and the anal fistula plug (AFP). However their overall mean …

BACKGROUND: The treatment of anal fistulas using plugs is a very promising method
because of its simplicity and ability to be carried out on an ambulatory basis. If unsuccessful …

Because of the morbidity associated with the performance of anal fistulotomy, especially that
of impairment for bowel control, less invasive options have been advocated in recent years …

Purpose: Long-term closure rates of anorectal fistulas using fibrin glue have been
disappointing, possibly because of the liquid consistency of the glue. A suturable …