Hypoxic-ischaemic encephalopathy (HIE) in termed infants remains a significant cause of
morbidity and mortality worldwide despite the introduction of therapeutic hypothermia …

Hypoxic–ischemic encephalopathy induces secondary brain injury characterized by delayed
energy failure. Currently, therapeutic hypothermia is the sole treatment available after …

The neuronal cell death associated with perinatal asphyxia, or hypoxic-ischemic (HI) brain
injury, plays an important role in neonatal mortality and neurodevelopment retardation. The …

Brain injury after hypoxic-ischemic encephalopathy often develops with delayed
appearance, opening a therapeutic window. Clinical studies in newborns show that post …

Perinatal hypoxic‐ischemic encephalopathy (HIE) is a significant cause of mortality and
morbidity in infants and young children. Therapeutic opportunities are very limited for …

The impact of birth asphyxia and its sequelae, hypoxic–ischaemic (HI) brain injury, is long-
lasting and significant, both for the infant and for their family. Treatment options are limited to …

Injury to the fragile immature brain is implicated in the manifestation of long-term
neurological disorders, including childhood disability such as cerebral palsy, learning …

Birth asphyxia in term neonates affects 1–2/1000 live births and results in the development
of hypoxic–ischaemic encephalopathy with devastating life-long consequences. The …

Hypoxic-ischemic encephalopathy, which predisposes to neonatal death and neurological
sequelae, has a high morbidity, but there is still a lack of effective prevention and treatment …

Neonatal hypoxic-ischemic encephalopathy is a critical cerebral event occurring around
birth with high mortality and neurological morbidity associated with long-term invalidating …