There is a compelling link between severe brain trauma and immunosuppression in patients
with traumatic brain injury (TBI). Although acute changes in the systemic immune …

BACKGROUND The complex alterations that occur in peripheral immunity after traumatic
brain injury (TBI) have been poorly characterized to date. The purpose of this study was to …

Central nervous system trauma is a common cause of morbidity and mortality. Additionally,
these injuries frequently occur in younger individuals, leading to lifetime expenses for …

Traumatic brain injury (TBI) affects an ever-growing population of all ages with long-term
consequences on health and cognition. Many of the issues that TBI patients face are thought …

Emerging evidence suggests that immune-inflammatory processes are key elements in the
physiopathological events associated with traumatic brain injury (TBI). TBI is followed by T …

Neuroinflammation is initiated as a result of traumatic brain injury and can exacerbate
evolving tissue pathology. Immune cells respond to acute signals from damaged cells …

Traumatic brain injury (TBI) is a leading cause of death and disability worldwide, and
typically involves a robust immune response. Although a great deal of preclinical research …

Traumatic injury to the brain (TBI) results in a complex set of responses involving various
symptoms and long-term consequences. TBI of any form can cause cognitive, behavioral …

Traumatic brain injury (TBI) is recognized as a global health problem due to its increasing
occurrence, challenging treatment, and persistent impacts on brain pathophysiology. Neural …

Abstract Treatment options for managing traumatic brain injury remain limited. Therapies
that limit the development of secondary brain injury—the delayed injury that can occur days …