Abstract Purpose of Review Ischemic cardiomyopathy refers to systolic left ventricular
dysfunction in the setting of obstructive coronary artery disease and represents the most …

As a result of the widespread use of reperfusion therapies and secondary prevention over
the last 30 years, there has been a dramatic reduction in the risk of mortality and …

ST-segment elevation myocardial infarction (STEMI) remains a significant source of
morbidity and mortality worldwide. Despite advances in treatment leading to a significant …

Opinion statement Patients with abnormalities of left ventricular (LV) systolic or diastolic
function may have no symptoms, especially in the early stages. These patients are not …

Chronic heart failure is a complex syndrome involving the activation of multiple cellular,
metabolic and neurohumoral pathways following the initial myocardial insult. Because of the …

Heart failure (HF) with reduced ejection fraction is common following acute myocardial
infarction (MI), and active medical management can have a profound impact on prognosis …

• The industry-sponsored, international, multicenter, randomized, double-blind, active-
comparator trial, PARADISE-MI 1 (Prospective ARNI vs. ACE Inhibitor Trial to Determine …

Importance Despite advances in cardiac care, patients remain at a high risk of death and the
development of heart failure (HF) following myocardial infarction (MI). These risks are …

Congestive heart failure is a leading cause of cardiovascular morbidity and mortality, and is
the main cause of hospitalization among patients older than 65 years. Moreover, its …