The Burden of Heart Failure

R Pratley, X Guan, RJ Moro, R do Lago - The American Journal of …, 2024 - Elsevier
Heart failure (HF) affects an estimated 6 million American adults, and the prevalence
continues to increase, driven in part by the aging of the population and by increases in the …

Overview of recent clinical trials in heart failure: what is the current standard of care?

DR MURRAY, J DUGAN - Cardiology in Review, 2000 - journals.lww.com
Heart failure develops as a consequence of cardiac injury. As the heart begins to fail to meet
the body's metabolic demands, the renin angiotensin aldosterone system (RAAS) and the …

Systolic heart failure: knowledge gaps, misconceptions, and future directions

R Samson, R Ramachandran, TH Le Jemtel - Ochsner Journal, 2014 - ochsnerjournal.org
Background Systolic heart failure is the final manifestation of several cardiovascular
conditions. The 2001 American College of Cardiology/American Heart Association …

The pathophysiology of myocardial infarction-induced heart failure

D Gabriel-Costa - Pathophysiology, 2018 - Elsevier
Heart failure (HF) is a multifactorial disorder and is usually the end stage of many
cardiovascular diseases (CVD). HF presents one of the highest morbidity and mortality …

Neurohormonal and cytokine activation in heart failure

DM McNamara - FUNDAMENTAL AND CLINICAL …, 2005 - api.taylorfrancis.com
Whether ischemic, viral, or inflammatory in etiology, the clinical syndrome of heart failure
begins with myocardial injury. The hemodynamic consequences of the initial injury elicit a …

Pharmacologic effects on cardiac remodeling

N Sharpe - Current Heart Failure Reports, 2004 - Springer
Clinical research during the past several decades has shown the importance of cardiac
remodeling as a basic mechanism in the progression of heart failure. Changes in cardiac …

Modern Approaches for the Treatment of Heart Failure: Recent Advances and Future Perspectives

IP Popa, MȘC Haba, MA Mărănducă, DM Tănase… - Pharmaceutics, 2022 - mdpi.com
Heart failure (HF) is a progressively deteriorating medical condition that significantly reduces
both the patients' life expectancy and quality of life. Even though real progress was made in …

Contemporary pharmacological treatment and management of heart failure

B Bozkurt - Nature Reviews Cardiology, 2024 - nature.com
The prevention and treatment strategies for heart failure (HF) have evolved in the past two
decades. The stages of HF have been redefined, with recognition of the pre-HF state, which …

Medical therapy for symptomatic heart failure: a contemporary treatment algorithm

SM Coronel, MJ Krantz - Critical Pathways in Cardiology, 2007 - journals.lww.com
Chronic heart failure is a relapsing condition resulting from structural or functional heart
disease that impedes either systolic or diastolic cardiac performance respectively. Heart …

Heart failure after myocardial infarction: clinical presentation and survival

JP Hellermann, SJ Jacobsen… - European journal of …, 2005 - Wiley Online Library
Objectives: To characterize the presentation and outcome of patients with heart failure (HF)
after myocardial infarction (MI) according to left ventricular ejection fraction (LVEF) and test …