New insights into Cryptococcus extracellular vesicles suggest a new structural model and an antifungal vaccine strategy

J Rizzo, SSW Wong, AD Gazi, F Moyrand, T Chaze… - BioRxiv, 2020 - biorxiv.org
Whereas extracellular vesicle (EV) research has become commonplace in different
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

Cryptococcus extracellular vesicles properties and their use as vaccine platforms

J Rizzo, SSW Wong, AD Gazi… - Journal of …, 2021 - Wiley Online Library
Whereas extracellular vesicle (EV) research has become commonplace in different
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

[PDF][PDF] Revisiting Cryptococcus extracellular vesicles properties and their use as vaccine platforms

J Rizzo, SSW Wong, AD Gazi, F Moyrand, T Chaze… - bioRxiv, 2021 - scholar.archive.org
Whereas extracellular vesicle (EV) research has become commonplace in different 35
biomedical fields, this field of research is still in its infancy in mycology. Here we provide a …

Nutritional Conditions Modulate C. neoformans Extracellular Vesicles' Capacity to Elicit Host Immune Response

CL Marina, PH Bürgel, DP Agostinho… - Microorganisms, 2020 - mdpi.com
Cryptococcus neoformans is a human pathogenic fungus that mainly afflicts
immunocompromised patients. One of its virulence strategies is the production of …

Elucidating the immunological function of the Cryptococcus neoformans capsule

A Vecchiarelli, E Pericolini, E Gabrielli… - Future …, 2013 - Future Medicine
The encapsulated fungal pathogen Cryptococcus neoformans represents a significant agent
of life-threatening infections in immunocompromised subjects. A unique characteristic of …

Capsules from Pathogenic and Non-Pathogenic Cryptococcus spp. Manifest Significant Differences in Structure and Ability to Protect against Phagocytic Cells

GS Araujo, FL Fonseca, B Pontes, A Torres… - PloS one, 2012 - journals.plos.org
Capsule production is common among bacterial species, but relatively rare in eukaryotic
microorganisms. Members of the fungal Cryptococcus genus are known to produce …

Pathogenic delivery: the biological roles of cryptococcal extracellular vesicles

HC de Oliveira, RF Castelli, FCG Reis, J Rizzo… - Pathogens, 2020 - mdpi.com
Extracellular vesicles (EVs) are produced by all domains of life. In fungi, these structures
were first described in Cryptococcus neoformans and, since then, they were characterized in …

Cryptococcus gattii evades CD11b‐mediated fungal recognition by coating itself with capsular polysaccharides

K Ueno, Y Otani, N Yanagihara, M Urai… - European Journal of …, 2021 - Wiley Online Library
Cryptococcus gattii is a capsular pathogenic fungus causing life‐threatening cryptococcosis.
Although the capsular polysaccharides (CPs) of C. gattii are considered as virulence factors …

The capsule of the fungal pathogen Cryptococcus neoformans

O Zaragoza, ML Rodrigues, M De Jesus… - Advances in applied …, 2009 - Elsevier
The capsule of the fungal pathogen Cryptococcus neoformans has been studied extensively
in recent decades and a large body of information is now available to the scientific …

Pathogen-derived extracellular vesicles mediate virulence in the fatal human pathogen Cryptococcus gattii

E Bielska, MA Sisquella, M Aldeieg, C Birch… - Nature …, 2018 - nature.com
Abstract The Pacific Northwest outbreak of cryptococcosis, caused by a near-clonal lineage
of the fungal pathogen Cryptococcus gattii, represents the most significant cluster of life …