Invasive fungal infections, including cryptococcosis, are a growing threat to
immunocompromised patients. Although Cryptococcus neoformans and Cryptococcus gattii …

Resistance to fluconazole (FLC), the most widely used antifungal drug, is typically achieved
by altering the azole drug target and/or drug efflux pumps. Recent reports have suggested a …

Extracellular vesicles (EVs) are now recognized as key players in the biology of numerous
organisms, including pathogenic fungi. However, studying EVs in these organisms remains …

Extracellular vesicles (EVs) produced by members of the Cryptococcus genus are
associated with fundamental processes of fungal physiology and virulence. However …

Cryptococcus neoformans is an encapsulated yeast and an opportunistic fungal pathogen
responsible for lifethreatening infections of the central nervous system (CNS) in HIV-1 …

The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

Extracellular vesicles (EVs) are lipidic nanosized particles that deliver a highly complex
molecular cargo between cells and organisms and may serve numerous functions in …

Cryptococcus neoformans produces vesicles containing its major virulence factor, the
capsular polysaccharide glucuronoxylomannan (GXM). These vesicles cross the cell wall to …

Small molecules are components of fungal extracellular vesicles (EVs), but their biological
roles are only superficially known. NOP16 is a eukaryotic gene that is required for the activity …

Exposure of Cryptococcus neoformans cells to gamma radiation results in a gradual release
of capsular polysaccharide, in a dose-dependent manner. This method allows the …