The Presence of Capsule in Cryptococcus neoformans Influences the Gene Expression Profile in Dendritic Cells during Interaction with the Fungus

P Lupo, YC Chang, BL Kelsall, JM Farber… - Infection and …, 2008 - Am Soc Microbiol
The aim of this investigation was to study the effect of polysaccharide capsule on the gene
expression in dendritic cells (DC) during their interaction with Cryptococcus neoformans. To …

[HTML][HTML] Immunomodulatory Role of Capsular Polysaccharides Constituents of Cryptococcus neoformans

D Decote-Ricardo, IF LaRocque-de-Freitas… - Frontiers in …, 2019 - frontiersin.org
Cryptococcosis is a systemic fungal infection caused by Cryptococcus neoformans. In
immunocompetent patients, cryptococcal infection is often confined to the lungs. In …

[HTML][HTML] The Cryptococcus wall: A different wall for a unique lifestyle

L Mukaremera - Plos Pathogens, 2023 - journals.plos.org
The life-threatening fungal pathogens Cryptococcus neoformans and Cryptococcus gattii are
differentiated from all other human fungal pathogens by the presence of a gelatinous …

Complementation of a Capsule-Deficient Mutation of Cryptococcus neoformans Restores its Virulence

YC Chang, KJ Kwon-Chung - Molecular and cellular biology, 1994 - Taylor & Francis
Capsule formation plays a significant role in the pathogenicity of Cryptococcus neoformans.
To study the molecular basis of capsule synthesis, the capsule-deficient phenotype of a …

The Intracellular Life of Cryptococcus neoformans

C Coelho, AL Bocca… - Annual Review of …, 2014 - annualreviews.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

How does Cryptococcus get its coat?

TL Doering - Trends in microbiology, 2000 - cell.com
During the past few decades, increasing attention has focused on pathogenic fungi both as
fascinating research subjects and as the agents of serious illness in diverse patient …

[HTML][HTML] Cell wall composition in Cryptococcus neoformans is media dependent and alters host response, inducing protective immunity

R Upadhya, WC Lam, CR Hole, JG Vasselli… - Frontiers in fungal …, 2023 - frontiersin.org
Introduction Cryptococcus neoformans is a basidiomycete fungus that can cause
meningoencephalitis, especially in immunocompromised patients. Cryptococcus grows in …

Unveiling Cryptosporidium parvum sporozoite-derived extracellular vesicles: profiling, origin, and protein composition

L Bertuccini, Z Boussadia, AM Salzano… - Frontiers in Cellular …, 2024 - frontiersin.org
Cryptosporidium parvum is a common cause of a zoonotic disease and a main cause of
diarrhea in newborns. Effective drugs or vaccines are still lacking. Oocyst is the infective …

Growth inhibition of Cryptococcus neoformans by cultured human monocytes: role of the capsule, opsonins, the culture surface, and cytokines

SM Levitz, TP Farrell - Infection and immunity, 1990 - Am Soc Microbiol
Despite a presumed critical role of macrophages in the host response to cryptococcal
infections, previous studies have failed to show growth inhibition of encapsulated …

[HTML][HTML] Scanning electron microscopy and machine learning reveal heterogeneity in capsular morphotypes of the human pathogen Cryptococcus spp.

W Lopes, GNF Cruz, ML Rodrigues, MH Vainstein… - Scientific Reports, 2020 - nature.com
Phenotypic heterogeneity is an important trait for the development and survival of many
microorganisms including the yeast Cryptococcus spp., a deadly pathogen spread …