Catch me if you can: phagocytosis and killing avoidance by Cryptococcus neoformans

R Garcia-Rodas, O Zaragoza - FEMS Immunology & Medical …, 2012 - academic.oup.com
After inhalation of infectious particles, Cryptococcus neoformans resides in the alveolar
spaces, where it can survive and replicate in the extracellular environment. This yeast has …

Human plasma-like medium (HPLM) induces Cryptococcus neoformans in vivo cell morphologies

E G. Mozo, O Ross, R Yuecel, IM Dambuza… - Msphere, 2024 - Am Soc Microbiol
The fungal pathogen Cryptococcus neoformans (C. neoformans) forms yeast cells of
different sizes and morphological characteristics during infection. These features are usually …

[HTML][HTML] Cryptococcus escapes host immunity: What do we know?

C Yang, Y Huang, Y Zhou, X Zang, H Deng… - Frontiers in Cellular …, 2022 - frontiersin.org
Cryptococcus is an invasive fungus that seriously endangers human life and health, with a
complex and well-established immune-escaping mechanism that interferes with the function …

Ingestion of acapsular Cryptococcus neoformans occurs via mannose and beta-glucan receptors, resulting in cytokine production and increased phagocytosis of the …

CE Cross, GJ Bancroft - Infection and immunity, 1995 - Am Soc Microbiol
Cryptococcus neoformans is a pathogenic yeast and a major cause of opportunistic infection
in AIDS patients. It is commonly found in an acapsular form in the environment, and infection …

Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival

O Zaragoza, CJ Chrisman, MV Castelli… - Cellular …, 2008 - Wiley Online Library
Cryptococcus neoformans is a facultative intracellular pathogen. The most distinctive feature
of C. neoformans is a polysaccharide capsule that enlarges depending on environmental …

A novel protocol for the isolation of fungal extracellular vesicles reveals the participation of a putative scramblase in polysaccharide export and capsule construction in …

FCG Reis, BS Borges, LJ Jozefowicz, BAG Sena… - MSphere, 2019 - Am Soc Microbiol
Regular protocols for the isolation of fungal extracellular vesicles (EVs) are time-consuming,
hard to reproduce, and produce low yields. In an attempt to improve the protocols used for …

[HTML][HTML] Characteristics and potential clinical applications of the extracellular vesicles of human pathogenic Fungi

A Ullah, Y Huang, K Zhao, Y Hua, S Ullah, M Rahman… - BMC microbiology, 2023 - Springer
Extracellular vesicles (EVs) are a heterogeneous group of lipid membrane-enclosed
compartments that contain different biomolecules and are released by almost all living cells …

Intracellular parasitism of macrophages by Cryptococcus neoformans

M Feldmesser, S Tucker, A Casadevall - Trends in microbiology, 2001 - cell.com
Cryptococcus neoformans, an encapsulated fungal pathogen, causes meningoencephalitis
in immunocompromised patients. Recent in vivo studies have demonstrated that C …

[HTML][HTML] Multiple Disguises for the Same Party: The Concepts of Morphogenesis and Phenotypic Variations in Cryptococcus neoformans

O Zaragoza - Frontiers in microbiology, 2011 - frontiersin.org
Although morphological transitions (such as hyphae and pseudohyphae formation) are a
common feature among fungi, the encapsulated pathogenic yeast Cryptococcus neoformans …

[HTML][HTML] Traveling into outer space: unanswered questions about fungal extracellular vesicles

ML Rodrigues, RMC Godinho, D Zamith-Miranda… - PLoS …, 2015 - journals.plos.org
Extracellular vesicle (EV) release in fungi was described for the first time in 2007 in the
yeastlike pathogen Cryptococcus neoformans [1]. Since then, the phenomenon of EV …