Cryptococcosis, a systemic mycosis that affects both the immunocompromised and
immunocompetent, is caused by the inhalation of dehydrated yeasts or fungal spores of …

Cryptococcus neoformans, an encapsulated, pathogenic yeast, is endowed with a variety of
virulence factors, including a polysaccharide capsule. During mammalian infection, the …

The human pathogen Cryptococcus neoformans causes meningo-encephalitis. The
polysaccharide capsule is an important virulence factor for this yeast-like fungus. Previously …

The fungal pathogen Cryptococcus neoformans has several virulence factors, among which
the most important is a polysaccharide capsule. The size of the capsule is variable and can …

Cryptococcus gattii is an emerging fungal pathogen on the west coast of Canada and the
United States that causes a potentially fatal infection in otherwise healthy individuals. In …

Phagosomal acidification is a critical cellular mechanism for the inhibition and killing of
ingested microbes by phagocytic cells. The acidic environment activates microbicidal …

Microbial capsules are important virulence traits that mediate cell-host interactions and
provide protection against host immune defense mechanisms. Cryptococcus neoformans is …

Disseminated infections with the fungal species Cryptococcus neoformans or, less
frequently, Cryptococcus gattii are an important cause of mortality in immunocompromised …

Three monoclonal antibodies (MAbs)(BA4, BD1, CD6) reacted with Cryptococcus
neoformans capsular glucuronoxylomannan (GXM) polysaccharide showing distinctive …

Background Cryptococcus neoformans is an encapsulated yeast that is a facultative
intracellular pathogen. The interaction between macrophages and C. neoformans is critical …