Secreted proteins from adipose tissue and skeletal muscle–adipokines, myokines and adipose/muscle cross-talk

P Trayhurn, CA Drevon, J Eckel - Archives of physiology and …, 2011 - Taylor & Francis
White adipose tissue and skeletal muscle are the largest organs in the body and both are
composed of distinct cell types. The signature cell of adipose tissue is the adipocyte while …

Metabolic and hormonal interactions between muscle and adipose tissue

E Tomas, M Kelly, X Xiang, TS Tsao… - Proceedings of the …, 2004 - cambridge.org
From the perspective of a muscle physiologist, adipose tissue has long been perceived
predominantly as a fuel reservoir that provides muscle and other tissues with NEFA when …

Myokines and adipokines: Involvement in the crosstalk between skeletal muscle and adipose tissue

F Li, Y Li, Y Duan, CAA Hu, Y Tang, Y Yin - Cytokine & growth factor …, 2017 - Elsevier
Skeletal muscle and adipose tissue are the two largest organs in the body. Skeletal muscle
is an effector organ, and adipose tissue is an organ that stores energy; in addition, they are …

Secretory factors from human adipose tissue and their functional role

H Hauner - Proceedings of the Nutrition Society, 2005 - cambridge.org
Obesity is characterized by an expanded adipose tissue mass. Recent data suggest that
adipose tissue is a multi-functional organ rather than simply a passive storage site for …

The adipocyte as an endocrine cell

N Halberg, I Wernstedt-Asterholm… - … and metabolism clinics of …, 2008 - Elsevier
Adipose tissue contains many cell types. Among the more abundant are adipocytes,
preadipocytes, immune cells, and endothelial cells. During times of excess caloric intake …

Cytokine secretion by human adipocytes is differentially regulated by adiponectin, AICAR, and troglitazone

H Sell, D Dietze-Schroeder, K Eckardt… - … and Biophysical Research …, 2006 - Elsevier
Adipose tissue is an active endocrine organ producing a variety of cytokines and
chemokines, which may be involved in the deregulation of glucose and lipid homeostasis as …

Exercise and regulation of adipokine and myokine production

SW Görgens, K Eckardt, J Jensen, CA Drevon… - Progress in molecular …, 2015 - Elsevier
Skeletal muscle and white adipose tissue are the largest organs in the human body and
both tissues act as endocrine organs capable of secreting many bioactive molecules. There …

Adipo‐myokines: Two sides of the same coin—Mediators of inflammation and mediators of exercise

S Raschke, J Eckel - Mediators of inflammation, 2013 - Wiley Online Library
This review summarizes the current literature regarding the most discussed contraction‐
regulated moykines like IL‐6, IL‐15, irisin, BDNF, ANGPTL4, FGF21, myonectin and MCP‐1 …

Cross‐talk between skeletal muscle and adipose tissue: a link with obesity?

JM Argilés, J López‐Soriano… - Medicinal research …, 2005 - Wiley Online Library
Since the discovery of leptin, the adipocyte and its products have been the subject of
intensive research. Thus, it has been demonstrated that adipose tissue plays a central role …

Minireview: the adipocyte—at the crossroads of energy homeostasis, inflammation, and atherosclerosis

MW Rajala, PE Scherer - Endocrinology, 2003 - academic.oup.com
Adipose tissue evolved to efficiently store energy for times of caloric restriction. The large
caloric excess common in many Western diets has negated the need for this thrifty function …