Psychedelics, also known as classical hallucinogens, have been investigated for decades
due to their potential therapeutic effects in the treatment of neuropsychiatric and substance …

Classical psychedelics are a group of drugs characterized by their activation of the serotonin-
2A (5-hydroxytryptamine-2A; 5-HT2A) receptor and the unique hallucinogenic and mystical …

Over the past decade, psychedelic compounds have emerged as potentially transformative
therapeutics for a variety of intractable neuropsychiatric conditions. However, historically …

The potential of psychedelics to persistently treat substance use disorders is known since
the 1960s. However, the biological mechanisms responsible for their therapeutic effects …

This paper provides a critical review of several possible mechanisms at different levels of
analysis underlying the effects and therapeutic potential of psychedelics. At the (1) …

Psychedelic research across different disciplines and biological levels is growing at a
remarkably fast pace. In the prospect of a psychedelic drug becoming again an approved …

Clinical studies suggest the therapeutic potential of psychedelics, including ayahuasca,
DMT, psilocybin, and LSD, in stress-related disorders. These substances induce cognitive …

Renewed interest in the use of psychedelics in the treatment of psychiatric disorders
warrants a better understanding of the neurobiological mechanisms underlying the effects of …

Psychedelics represent one of the most promising classes of experimental medicines for the
treatment of neuropsychiatric disorders due to their ability to promote neural plasticity and …

Psychedelic drugs including psilocybin, N, N ʹ-dimethyltryptamine (DMT) and lysergic acid
diethylamide (LSD) are undergoing a renaissance as potentially useful drugs for various …