Peripheral nerve injuries (PNIs) frequently occur due to various factors, including
mechanical trauma such as accidents or tool-related incidents, as well as complications …

This chapter presents an overview of basic principles related to neuronal responses to injury
and disease in the peripheral and central nervous systems (PNS and CNS, respectively) …

The aging peripheral nervous system (PNS) is prone to a number of disorders, including the
development of neuropathies and increased regenerative failure. Although the basic …

Peripheral nerve injury is common especially among young individuals. Although injured
neurons have the ability to regenerate, the rate is slow and functional outcomes are often …

Schwann cells develop from the neural crest in a well-defined sequence of events. This
involves the formation of the Schwann cell precursor and immature Schwann cells, followed …

Schwann cells are glial cells that are responsible for the synthesis and maintenance of the
myelin sheath in the peripheral nerve system. Under pathological conditions, such as …

Peripheral nerves are functional networks in the body. Disruption of these networks induces
varied functional consequences depending on the types of nerves and organs affected …

This review will address new ideas, including several from our laboratory, on the role of local
molecules and signaling within the microenvironment of injured peripheral nerve trunks …

Schwann cell incredible plasticity is a hallmark of the utmost importance following nerve
damage or in demyelinating neuropathies. After injury, Schwann cells undergo …

Whereas the central nervous system (CNS) usually cannot regenerate, peripheral nerves
regenerate spontaneously after injury because of a permissive environment and activation …