Gonococcal defenses against antimicrobial activities of neutrophils

A Palmer, AK Criss - Trends in microbiology, 2018 - cell.com
Neisseria gonorrhoeae initiates a strong local immune response that is characterized by
copious recruitment of neutrophils to the site of infection. Neutrophils neutralize microbes by …

[HTML][HTML] Resistance of Neisseria Gonorrhoeae to Neutrophils

MB Johnson, AK Criss - Frontiers in microbiology, 2011 - frontiersin.org
Infection with the human-specific bacterial pathogen Neisseria gonorrhoeae triggers a
potent, local inflammatory response driven by polymorphonuclear leukocytes (neutrophils or …

[HTML][HTML] Mechanisms of host manipulation by Neisseria gonorrhoeae

E Walker, S van Niekerk, K Hanning, W Kelton… - Frontiers in …, 2023 - frontiersin.org
Neisseria gonorrhoeae (also known as gonococcus) has been causing gonorrhoea in
humans since ancient Egyptian times. Today, global gonorrhoea infections are rising at an …

Interactions of Neisseria gonorrhoeae with human neutrophils

RF Rest, WM Shafer - Clinical microbiology reviews, 1989 - Am Soc Microbiol
The hallmark of acute gonococcal urethritis in males is the presence of gram-negative
intracellular diplococci. Not only has this observation served as a diagnostic indication of …

A bacterial siren song: intimate interactions between Neisseria and neutrophils

AK Criss, HS Seifert - Nature Reviews Microbiology, 2012 - nature.com
Neisseria gonorrhoeae and Neisseria meningitidis are Gram-negative bacterial pathogens
that are exquisitely adapted for growth at human mucosal surfaces and for efficient …

Neisseria gonorrhoeae elicits extracellular traps in primary neutrophil culture while suppressing the oxidative burst

CW Gunderson, HS Seifert - MBio, 2015 - Am Soc Microbiol
Neisseria gonorrhoeae (the gonococcus) causes gonorrhea and is uniquely adapted to
survive within the human reproductive tract. Gonococci evade host immune surveillance in …

Neisseria gonorrhoeae phagosomes delay fusion with primary granules to enhance bacterial survival inside human neutrophils

MB Johnson, AK Criss - Cellular microbiology, 2013 - Wiley Online Library
Symptomatic infection with N eisseria gonorrhoeae (Gc) promotes inflammation driven by
polymorphonuclear leucocytes (PMN s, neutrophils), yet some Gc survive PMN exposure …

[HTML][HTML] Macrophage–Neisseria gonorrhoeae Interactions: A Better Understanding of Pathogen Mechanisms of Immunomodulation

A Escobar, PI Rodas, C Acuña-Castillo - Frontiers in immunology, 2018 - frontiersin.org
Neisseria gonorrhoeae is a significant health problem worldwide due to multi-drug
resistance issues and absence of an effective vaccine. Patients infected with N …

Neisseria gonorrhoeae survives within and modulates apoptosis and inflammatory cytokine production of human macrophages

A Château, HS Seifert - Cellular microbiology, 2016 - Wiley Online Library
The human‐adapted organism Neisseria gonorrhoeae is the causative agent of gonorrhoea,
a sexually transmitted infection. It readily colonizes the genital, rectal and nasalpharyngeal …

[HTML][HTML] Commensal Neisseria species share immune suppressive mechanisms with Neisseria gonorrhoeae

W Zhu, MX Cardenas-Alvarez, J Tomberg, MB Little… - Plos one, 2023 - journals.plos.org
Neisseria gonorrhoeae is a highly adapted human sexually transmitted pathogen that can
cause symptomatic infections associated with localized inflammation as well as …