[HTML][HTML] Development of an mrna-lnp vaccine against sars-Cov-2: Evaluation of immune response in mouse and rhesus macaque
Among the vaccines have been developed thus far against SARS-CoV-2, the mRNA-based
ones have demonstrated more promising results regarding both safety and efficacy. Two …
ones have demonstrated more promising results regarding both safety and efficacy. Two …
Single‐cell transcriptome atlas reveals protective characteristics of COVID‐19 mRNA vaccine
Y Tan, S Lu, B Wang, X Duan, Y Zhang… - Journal of Medical …, 2023 - Wiley Online Library
Messenger RNA (mRNA) vaccines are promising alternatives to conventional vaccines in
many aspects. We previously developed a lipopolyplex (LPP)‐based mRNA vaccine …
many aspects. We previously developed a lipopolyplex (LPP)‐based mRNA vaccine …
Nonclinical safety assessment of an mRNA Covid‐19 vaccine candidate following repeated administrations and biodistribution
K Broudic, S Laurent, V Perkov, C Simon… - Journal of Applied …, 2024 - Wiley Online Library
Messenger RNA (mRNA) vaccines have demonstrated efficacy against Severe Acute
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) in humans. mRNA technology holds …
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) in humans. mRNA technology holds …
mRNA vaccine mitigates SARS-CoV-2 infections and COVID-19
CM Kackos, SL Surman, BG Jones, RE Sealy… - Microbiology …, 2023 - Am Soc Microbiol
The novel coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
was identified in December of 2019 and is responsible for millions of infections and deaths …
was identified in December of 2019 and is responsible for millions of infections and deaths …
[HTML][HTML] mRNA-based vaccines and therapeutics: an in-depth survey of current and upcoming clinical applications
YS Wang, M Kumari, GH Chen, MH Hong… - Journal of Biomedical …, 2023 - Springer
Abstract mRNA-based drugs have tremendous potential as clinical treatments, however, a
major challenge in realizing this drug class will promise to develop methods for safely …
major challenge in realizing this drug class will promise to develop methods for safely …
[HTML][HTML] A comprehensive review of mRNA vaccines
mRNA vaccines have been demonstrated as a powerful alternative to traditional
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …
conventional vaccines because of their high potency, safety and efficacy, capacity for rapid …
Split-dose administration enhances immune responses elicited by a mRNA/lipid nanoparticle vaccine expressing respiratory syncytial virus F protein
mRNA vaccines have recently received significant attention due to their role in combating
the SARS-CoV-2 pandemic. As a platform, mRNA vaccines have been shown to elicit strong …
the SARS-CoV-2 pandemic. As a platform, mRNA vaccines have been shown to elicit strong …
[HTML][HTML] RNA vaccines: a suitable platform for tackling emerging pandemics?
JB Sandbrink, RJ Shattock - Frontiers in Immunology, 2020 - frontiersin.org
The COVID-19 pandemic demonstrates the ongoing threat of pandemics caused by novel,
previously unrecognized, or mutated pathogens with high transmissibility. Currently, vaccine …
previously unrecognized, or mutated pathogens with high transmissibility. Currently, vaccine …
Effectiveness of a broad-spectrum bivalent mRNA vaccine against SARS-CoV-2 variants in preclinical studies
J Lu, S Tan, H Gu, K Liu, W Huang, Z Yu… - Emerging Microbes & …, 2024 - Taylor & Francis
Vaccines utilizing modified messenger RNA (mRNA) technology have shown robust
protective efficacy against SARS-CoV-2 in humans. As the virus continues to evolve in both …
protective efficacy against SARS-CoV-2 in humans. As the virus continues to evolve in both …
[HTML][HTML] Self-replicating RNA nanoparticle vaccine elicits protective immune responses against SARS-CoV-2
G Lin, H Yan, J Sun, J Zhao, Y Zhang - Molecular Therapy-Nucleic Acids, 2023 - cell.com
The creation of safe and effective vaccines that induce potent cellular and humoral immune
responses against SARS-CoV-2 is urgently needed to end the global COVID-19 epidemic …
responses against SARS-CoV-2 is urgently needed to end the global COVID-19 epidemic …