Helicases are ubiquitous enzymes that disrupt complementary strands of duplex nucleic
acid in a reaction dependent on nucleoside-5′-triphosphate hydrolysis. Helicases are …

Most processes involving an organism's genetic material, including replication, repair and
recombination, require access to single-stranded DNA as a template or reaction …

DNA helicases are a class of enzymes able to unwind the two complementary DNA strands
in a reaction dependent on energy derived from nucleoside 5!-triphosphate hydrolysis. Their …

Since the discovery of the DNA double helix, there has been a fascination in understanding
the molecular mechanisms and cellular processes that account for:(i) the transmission of …

In this special Methods collection on DNA helicases, I have solicited articles from leading
experts in the field with a priority to gather a defined series of papers on highly relevant …

Unwinding of double-stranded DNA is required to create a single-stranded DNA template for
essential DNA processes such as those involved in recombination, repair, and replication. A …

The unwinding of duplex DNA is a prerequisite for DNA relication and repair, providing the
Single-Stranded DNA (ssDNA) template for DNA polymerase to copy. Duplex DNA must …

DNA helicases are molecular motors that harness the energy of nucleoside triphosphate
hydrolysis to unwinding structured DNA molecules that must be resolved during cellular …

First discovered in the 1970s, DNA helicases were initially described as enzymes that use
chemical energy to separate (ie, to unwind) the complementary strands of DNA. Because …

DNA helicases have emerged as a prominent class of nucleic acid-metabolizing enzymes
that play important roles in genome maintenance and cellular homeostasis. DNA helicases …