The obesity paradox in multiple myeloma: A report from Multiple Myeloma Research Foundation (MMRF) dataset

L Ren, T Xu, Y Ren, P Liu - Cancer Medicine, 2023 - Wiley Online Library
Background Obesity is a risk factor for multiple myeloma (MM). However, we still lack
knowledge on the clinical course of obese MM patients in a broad view. Methods Here, we …

Influence of obesity on outcomes of patients with relapsed refractory multiple myeloma

V Roy, A Swaika, S Kumar… - Clinical …, 2017 - clinical-lymphoma-myeloma …
Conclusion In patients with heavily pretreated multiple myeloma obesity (BMI 30 or more)
was associated with better outcomes compared to BMI< 30. Response rate was similar in …

Decreased body mass index is associated with poor prognosis in patients with multiple myeloma

SH Jung, DH Yang, JS Ahn, SS Lee, SY Ahn… - Annals of …, 2014 - Springer
Obesity increases morbidity in and mortality of patients with various types of cancer.
However, the proportion of obese individuals in Asia is smaller than that in Western …

FDA analysis: Impact of BMI on efficacy outcomes in multiple myeloma trials.

R Ershler, LL Fernandes, B Kanapuru, T Gwise… - 2020 - ascopubs.org
8543 Background: Obesity has been implicated as a risk factor for the development of
certain types of cancers, including multiple myeloma. Previous studies in other tumor types …

[HTML][HTML] Body mass index and overall survival of patients with newly diagnosed multiple myeloma

B Wang, BA Derman, SS Langerman, J Johnson… - Cancers, 2022 - mdpi.com
Simple Summary There is a growing need to clarify the effect of modifiable lifestyle factors
such as obesity on outcomes of multiple myeloma (MM). In this paper, we examined the …

Obesity and multiple myeloma: Emerging mechanisms and perspectives

A Tentolouris, I Ntanasis-Stathopoulos… - Seminars in Cancer …, 2023 - Elsevier
Obesity is a global pandemic that has been associated with the development of breast,
endometrial, large intestine, renal, esophageal, and pancreatic cancer. Obesity is also …

Obesity and multiple myeloma

T Beason, G Colditz - Energy Balance and Hematologic Malignancies, 2012 - Springer
Multiple myeloma (MM) is a plasma B-cell malignancy that is characterized by the presence
of clonal proliferation of malignant plasma cells in the bone marrow, monoclonal protein in …

Underweight as a risk factor of mortality in patients with newly diagnosed multiple myeloma

CK Tsai, CM Yeh, TL Hsu, CJ Li, C Tin, LT Hsiao… - Supportive Care in …, 2021 - Springer
Purpose Multiple myeloma (MM), a clonal plasma cell malignancy, composes around 10%
of hematologic malignancies. Though recent advances in treatment have dramatically …

[PDF][PDF] Obesity as a risk factor for multiple myeloma: Insight on the role of adipokines

W Tie, T Ma, Z Yi, J Liu, Y Li, J Bai, L Li… - Pathology and …, 2023 - por-journal.com
Multiple myeloma (MM) is a blood cancer of abnormal clonal plasma cells in the bone
marrow. MM accounts for 1% of neoplastic diseases and is the second most common …

The skinny on obesity and plasma cell myeloma: a review of the literature

KR Carson, ML Bates, MH Tomasson - Bone marrow transplantation, 2014 - nature.com
Despite tremendous advances in treatments for myeloma in the past decade, the disease
remains incurable in the majority of patients. Here, we review recent data demonstrating an …