Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample

KS Kendler, G Kalsi, PA Holmans… - Alcoholism: Clinical …, 2011 - Wiley Online Library
Background: While genetic influences on alcohol dependence (AD) are substantial,
progress in the identification of individual genetic variants that impact on risk has been …

Genome-wide association study of alcohol dependence

J Treutlein, S Cichon, M Ridinger… - Archives of general …, 2009 - jamanetwork.com
Context Alcohol dependence is a serious and common public health problem. It is well
established that genetic factors play a major role in the development of this disorder …

Genome-wide association study of alcohol dependence: significant findings in African-and European-Americans including novel risk loci

J Gelernter, HR Kranzler, R Sherva, L Almasy… - Molecular …, 2014 - nature.com
We report a GWAS of alcohol dependence (AD) in European-American (EA) and African-
American (AA) populations, with replication in independent samples of EAs, AAs and …

Genome‐wide analysis reveals genetic overlap between alcohol use behaviours, schizophrenia and bipolar disorder and identifies novel shared risk loci

ED Wiström, KS O'Connell, N Karadag, S Bahrami… - …, 2022 - Wiley Online Library
Background and aim Schizophrenia (SCZ) and bipolar disorder (BD) have a high
comorbidity of alcohol use disorder (AUD), and both comorbid AUD and excessive alcohol …

Alcohol dependence genetics: lessons learned from genome‐wide association studies (GWAS) and post‐GWAS analyses

AB Hart, HR Kranzler - Alcoholism: clinical and experimental …, 2015 - Wiley Online Library
Background Alcohol dependence (AD) is a complex psychiatric disorder and a significant
public health problem. Twin and family‐based studies have consistently estimated its …

The genetics of alcohol dependence: Twin and SNP‐based heritability, and genome‐wide association study based on AUDIT scores

H Mbarek, Y Milaneschi, IO Fedko… - American Journal of …, 2015 - Wiley Online Library
Alcohol dependence (AD) is among the most common and costly public health problems
contributing to morbidity and mortality throughout the world. In this study, we investigate the …

[HTML][HTML] Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q

L Zuo, J Gelernter, CK Zhang, H Zhao, L Lu… - …, 2012 - nature.com
Previous studies using SAGE (the Study of Addiction: Genetics and Environment) and COGA
(the Collaborative Study on the Genetics of Alcoholism) genome-wide association study …

Item-level genome-wide association study of the alcohol use disorders identification test in three population-based cohorts

TT Mallard, JE Savage, EC Johnson… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Genome-wide association studies (GWASs) of the Alcohol Use Disorders
Identification Test (AUDIT), a 10-item screen for alcohol use disorder (AUD), have elucidated …

Genomewide association study of alcohol dependence and related traits in a Thai population

J Gelernter, H Zhou, YZ Nuñez… - Alcoholism: clinical …, 2018 - Wiley Online Library
Background Alcohol use (both quantity and dependence) is moderately heritable, and
genomewide association studies (GWAS) have identified risk genes in European, African …

Using genetic information from candidate gene and genome‐wide association studies in risk prediction for alcohol dependence

J Yan, F Aliev, BT Webb, KS Kendler… - Addiction …, 2014 - Wiley Online Library
Family‐based and genome‐wide association studies (GWAS) of alcohol dependence (AD)
have reported numerous associated variants. The clinical validity of these variants for …