It is now well established that nerve growth factor (NGF) plays a key role in inflammation-
induced hyperalgesia. It was also reported that brain derived neurotrophic factor (BDNF) …

Neurotrophic factors, such as nerve growth factor and brain-derived neurotrophic factor, are
members of the structurally related neurotrophin family that play important roles in pain …

To reveal roles of neurotrophic factors in plastic changes of the primary afferent neurons
following nerve injury, we investigated expression of glial cell line-derived neurotrophic …

It is well known that the nerve growth factor (NGF) may serve as a link between inflammation
and hyperalgesia. Recent experiments showed that systemic injection of NGF dramatically …

Key points Nerve growth factor (NGF) and glial cell line‐derived neurotrophic factor (GDNF)
are essential for neuronal development and survival in embryo. However, after birth they …

Aims This study was aimed to explore the contribution of central brain-derived neurotrophic
factor (BDNF) in the neuropathic pain pathogenesis using an aged rodent model. Main …

Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are two major
members of the neurotrophin family. Using immunohistochemistry and in situ hybridization …

Neuropathic pain is initiated by a primary lesion in the peripheral nervous system and spoils
quality of life. Neurotrophins play important roles in the development and transmission of …

Nerve growth factor (NGF), a member of the neurotrophin family, is essential for the
development and maintenance of sensory neurons and for the formation of central pain …

In an attempt to clarify whether glial cell line‐derived neurotrophic factor (GDNF), a survival
factor for subpopulations of primary afferent neurons, is involved in the states of neuropathic …