A pilot study to assess the effect of acute exercise on brain glutathione

S Rai, A Chowdhury, RLEP Reniers, SJ Wood… - Free radical …, 2018 - Taylor & Francis
The brain is highly susceptible to oxidative stress due to its high metabolic demand.
Increased oxidative stress and depletion of glutathione (GSH) are observed with aging and …

Effects of a maximal graded exercise test on glutathione as a marker of acute oxidative stress

AS Elokda, RK Shields, DH Nielsen - Journal of Cardiopulmonary …, 2005 - journals.lww.com
PURPOSE Strenuous exercise in animal studies has been shown to cause acute oxidative
stress due to the generation of oxygen-centered free radicals reflected in lower levels of …

[HTML][HTML] Changes in levels of the antioxidant glutathione in brain and blood across the age span of healthy adults: A systematic review

F Detcheverry, S Senthil, S Narayanan… - NeuroImage: Clinical, 2023 - Elsevier
Aging is characterized by a gradual decline of the body's biological functions, which can
lead to increased production of reactive oxygen species (ROS). Antioxidants neutralize ROS …

Brain oxidative stress: detection and mapping of anti-oxidant marker 'Glutathione'in different brain regions of healthy male/female, MCI and Alzheimer patients using …

PK Mandal, M Tripathi, S Sugunan - Biochemical and biophysical research …, 2012 - Elsevier
Glutathione (GSH) serves as an important anti-oxidant in the brain by scavenging harmful
reactive oxygen species that are generated during different molecular processes. The GSH …

In vivo brain GSH: MRS methods and clinical applications

F Bottino, M Lucignani, A Napolitano, F Dellepiane… - Antioxidants, 2021 - mdpi.com
Glutathione (GSH) is an important antioxidant implicated in several physiological functions,
including the oxidation− reduction reaction balance and brain antioxidant defense against …

[HTML][HTML] Quantification of glutathione in the human brain by MR spectroscopy at 3 Tesla: Comparison of PRESS and MEGA‐PRESS

FS Nezhad, A Anton, LM Parkes, B Deakin… - Magnetic resonance …, 2017 - ncbi.nlm.nih.gov
Purpose Glutathione (GSH) is an important intracellular antioxidant in the brain. A number of
studies report its measurement by localized 1 H spectroscopy using PRESS and STEAM …

Quantification of glutathione in the human brain by MR spectroscopy at 3 T esla: Comparison of PRESS and MEGA‐PRESS

F Sanaei Nezhad, A Anton, LM Parkes… - Magnetic …, 2017 - Wiley Online Library
Purpose Glutathione (GSH) is an important intracellular antioxidant in the brain. A number of
studies report its measurement by localized 1H spectroscopy using PRESS and STEAM …

In vivo brain glutathione is higher in older age and correlates with mobility

KE Hupfeld, HW Hyatt, P Alvarez Jerez… - Cerebral …, 2021 - academic.oup.com
Brain markers of oxidative damage increase with advancing age. In response, brain
antioxidant levels may also increase with age, although this has not been well investigated …

[PDF][PDF] Physical exercise intensity can be related to plasma glutathione levels

C Gambelunghe, R Rossi, A Micheletti… - Journal of physiology …, 2001 - researchgate.net
The aim of the present study was to examine the effect of different kinds of physical exercise
on plasma glutathione levels. Male Wistar rats were randomly divided into four groups: In …

Contribution of reduced and oxidized glutathione to signals detected by magnetic resonance spectroscopy as indicators of local brain redox state

T Satoh, Y Yoshioka - Neuroscience research, 2006 - Elsevier
The reduced form of glutathione (GSH; γ-glutamyl cysteinyl glycine) is supposedly the most
powerful reducing battery in the central nervous system against oxidative stress. We …