Clear cell renal cell carcinoma (ccRCC) is known as the most aggressive subtype of
genitourinary cancers. The lack of effective therapies has prompted us to further explore the …

Abstract Interleukin-4 (IL-4) and IL-13 are anti-inflammatory and immunoregulatory cytokines
that can influence cancer-directed immunosurveillance. However, they are not evaluated as …

Background: Traditional clinicopathological features (TNM, pathology grade) are often
insufficient in predictive prognosis accuracy of clear cell renal cell carcinoma (ccRCC). The …

Specific kinds of interleukin (IL) receptors are known to mediate lymphocyte proliferation and
survival. However, recent reports have suggested that the high expression of IL4Rα and …

Recently studies have identified a critical role for interferon regulatory factor (IRF) in
modulating tumour immune microenvironment (TME) infiltration and tumorigenesis. Based …

Background Growing findings have demonstrated that interferon regulatory transcription
factor (IRF) family members are linked to the progression of various cancers. However, the …

Background. Clear cell renal cell carcinoma (ccRCC) is a type of life‐threatening malignant
tumor of the urinary system. IL20RB, interleukin 20 receptor subunit beta, is a cytokine …

Kidney renal clear cell carcinoma (KIRC) is one of the most common cancers globally, with
an overall poor prognosis. The Janus kinase (JAK) family plays an essential role in cellular …

BACKGROUND: Renal cell carcinoma (RCC) is the highest mortality rate of the
genitourinary cancers, and the treatment options are very limited. Thus, identification of …

MicroRNAs (miRNA) that are strongly implicated in carcinogenesis have recently reshaped
our understanding of the role of noncoding RNAs. Here, we focused on the function and …