METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to …
Y Zhu, X Peng, Q Zhou, L Tan, C Zhang, S Lin… - Cell death & …, 2022 - nature.com
Papillary thyroid cancer (PTC) is a common endocrine system malignancy all over the world.
Aberrant expression of six transmembrane epithelial antigen of the prostate 2 (STEAP2) has …
Aberrant expression of six transmembrane epithelial antigen of the prostate 2 (STEAP2) has …
FTO prevents thyroid cancer progression by SLC7A11 m6A methylation in a ferroptosis-dependent manner
FH Ji, XH Fu, GQ Li, Q He, XG Qiu - Frontiers in Endocrinology, 2022 - frontiersin.org
N6 methyladenosine (m6A) modification serves as a novel epigenetic regulatory mechanism
that is heavily implicated in the heredity of tumors. Meanwhile, fat mass and obesity …
that is heavily implicated in the heredity of tumors. Meanwhile, fat mass and obesity …
METTL3 restrains papillary thyroid cancer progression via m6A/c-Rel/IL-8-mediated neutrophil infiltration
J He, M Zhou, J Yin, J Wan, J Chu, J Jia, J Sheng… - Molecular Therapy, 2021 - cell.com
Growing evidence indicates that N6-methyladenosine (m 6 A) is the most pervasive RNA
modification in eukaryotic cells. However, the specific role of METTL3 in papillary thyroid …
modification in eukaryotic cells. However, the specific role of METTL3 in papillary thyroid …
METTL14 promotes prostate tumorigenesis by inhibiting THBS1 via an m6A-YTHDF2-dependent mechanism
Y Wang, J Chen, WQ Gao, R Yang - Cell death discovery, 2022 - nature.com
Abstract N6-methyladenine (m6A) is the most predominant RNA modification, which has
been shown to be related to many types of cancers. However, understanding of its role in …
been shown to be related to many types of cancers. However, understanding of its role in …
METTL14 promotes tumorigenesis by regulating lncRNA OIP5-AS1/miR-98/ADAMTS8 signaling in papillary thyroid cancer
X Zhang, D Li, C Jia, H Cai, Z Lv, B Wu - Cell death & disease, 2021 - nature.com
Background Papillary thyroid cancer (PTC) is the most common type of cancer of the
endocrine system. Long noncoding RNAs (lncRNAs) are emerging as a novel class of gene …
endocrine system. Long noncoding RNAs (lncRNAs) are emerging as a novel class of gene …
Progression of Thyroid Carcinoma Is Promoted by the m6A Methyltransferase METTL3 Through Regulating m6A Methylation on TCF1
K Wang, L Jiang, Y Zhang, C Chen - OncoTargets and therapy, 2020 - Taylor & Francis
Objective This study aims to uncover the progression of thyroid carcinoma influenced by the
m6A methyltransferase METTL3 through regulating m6A methylation on TCF1 mRNA and …
m6A methyltransferase METTL3 through regulating m6A methylation on TCF1 mRNA and …
LDHA induces EMT gene transcription and regulates autophagy to promote the metastasis and tumorigenesis of papillary thyroid carcinoma
Papillary thyroid carcinoma (PTC) is one of the most common kinds of endocrine-related
cancer and has a heterogeneous prognosis. Metabolic reprogramming is one of the …
cancer and has a heterogeneous prognosis. Metabolic reprogramming is one of the …
Knockdown of STEAP1 inhibits cell growth and induces apoptosis in LNCaP prostate cancer cells counteracting the effect of androgens
IM Gomes, SM Rocha, C Gaspar, MI Alvelos… - Medical Oncology, 2018 - Springer
Six transmembrane epithelial antigen of the prostate 1 (STEAP1) is overexpressed in
numerous types of tumors, especially in prostate cancer. STEAP1 is located in the plasma …
numerous types of tumors, especially in prostate cancer. STEAP1 is located in the plasma …
STEAP3 promotes cancer cell proliferation by facilitating nuclear trafficking of EGFR to enhance RAC1-ERK-STAT3 signaling in hepatocellular carcinoma
LL Wang, J Luo, ZH He, YQ Liu, HG Li, D Xie… - Cell Death & …, 2021 - nature.com
STEAP3 (Six-transmembrane epithelial antigen of the prostate 3, TSAP6, dudulin-2) has
been reported to be involved in tumor progression in human malignancies. Nevertheless …
been reported to be involved in tumor progression in human malignancies. Nevertheless …
RNA m6A Methyltransferase METTL3 Promotes The Growth Of Prostate Cancer By Regulating Hedgehog Pathway
J Cai, F Yang, H Zhan, J Situ, W Li, Y Mao… - OncoTargets and …, 2019 - Taylor & Francis
Purpose N6-methyladenosine (m6A) is the most abundant internal modification on
eukaryotic mRNA and gained increasing attention recently. More and more evidence …
eukaryotic mRNA and gained increasing attention recently. More and more evidence …