Depression and anxiety are common and often comorbid mental health disorders that
represent risk factors for aging-related conditions. Brain aging has shown to be more …

Major depressive disorder (MDD) is associated with an increased risk of brain atrophy,
aging-related diseases, and mortality. We examined potential advanced brain aging in adult …

Depression is associated with markers of accelerated aging, but it is unclear how this
relationship changes across the lifespan. We examined whether a brain-based measure of …

Objectives Previous studies suggest that major depressive disorder (MDD) may be
associated with volumetric indications of accelerated brain aging. This study investigated …

Molecular biological findings indicate that affective disorders are associated with processes
akin to accelerated aging of the brain. The use of the BrainAGE (brain age estimation gap) …

Major depressive disorder (MDD) is one of the most common mental health conditions that
has been intensively investigated for its association with brain atrophy and mortality. Recent …

Background Several studies have evaluated whether depressed persons have older
appearing brains than their nondepressed peers. However, the estimated neuroimaging …

Depression associated with structural brain abnormalities is hypothesized to be related with
accelerated brain aging. However, there is far from a unified conclusion because of clinical …

Multiple structural and functional neuroimaging measures vary over the course of the
lifespan and can be used to predict chronological age. Accelerated brain aging, as …

Objective To evaluate whether accelerated brain aging occurs in individuals with mood or
psychotic disorders. Methods A systematic review following PRISMA guidelines was …