Regular physical activity not only improves the exercise capacity of the skeletal muscle
performing the contractions, but it is beneficial for the whole body. An extensive search for …

The underlying mechanisms responsible for mediating the beneficial outcomes of exercise
undoubtedly are many, but the insulin-like growth factor-I (IGF-I) system is emerging as an …

Introduction: Myokines, known to mediate metabolism, inflammation, and other
pathophysiological conditions, have been widely investigated, including myokines induced …

Naturally occurring physical activity in humans plays a profound role in tissue anabolism,
growth, and development, yet little is known about the mechanisms that link patterns of …

Exercise is known to prevent and treat metabolic diseases such as diabetes. However, the
underlying mechanisms are not fully understood, and there is currently much focus on …

The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

The concentration of plasma interleukin (IL)-6 increases during physical exercise and recent
research identifies skeletal muscle as an endocrine organ, which is the major source of the …

Purpose Exercise health benefits are partly mediated by exertional changes in several
myokines/adipokines. This study aimed to compare the acute response of some of these …

The beneficial effects of exercise on the proper functioning of the body have been firmly
established. Multi-systemic metabolic regulation of exercise is the consequence of …