Although the efficacy of amiodarone in the treatment of drug refractory cardiac arrhythmias is
firmly established, the same cannot be said for the dosage. Amiodarone has been described …

The purpose of the present report is to review the available pharmacokinetic informaation on
amiodarone with an emphasis on our own experience in monitoring serum amiodarone …

Amiodarone is an iodinated benzofuran derivative with recognised antiarrhythmic activity in
man. As yet, its pharmacokinetic behaviour has not been satisfactorily characterised …

Amiodarone is a useful antiarrhythmic agent whose pharmacokinetics are incompletely
characterised. In order to optimise efficacy of an antiarrhythmic drug, information regarding …

Amiodarone is the most effective agent in the therapy of arrhythmias. However, the clinical
effect of acute and chronic treatment is unclear and there are differences irrespective of …

The available data concerning amiodarone dosing may be summarized as follows:(1) There
is an empirically demonstrated improvement in lag before onset of antiarrhythmic effect if …

Amiodarone serum kinetics after single oral doses and after long‐term therapy were
investigated in patients with ventricular tachyarrhythmias. When amiodarone was given as a …

This article attempts to provide an overview of the present knowledge of the
pharmacokinetics of amiodarone and how this relates to the clinical usage of oral …

Amiodarone is a complex molecule with multiple pharmacologic properties and a complex
electrophysiologic profile. Its disposition kinetics and relation between plasma drug …

Using a high-pressure liquid chromatographic assay, we measured serum amiodarone
concentrations serially in 122 patients treated with amiodarone for 1.5-53 months (mean 9.3 …