Minimizing time to optimal antimicrobial therapy for Enterobacteriaceae bloodstream infections: a retrospective, hypothetical application of predictive scoring tools vs …

LN Cwengros, RP Mynatt, TT Timbrook… - Open Forum …, 2020 - academic.oup.com
Abstract Background Bloodstream infections (BSIs) due to ceftriaxone (CRO)-resistant
Enterobacteriaceae are associated with delays in time to appropriate therapy and worse …

Comparative analysis of a rapid diagnostic test and scoring tools for ESBL detection in Enterobacterales bloodstream infections for optimizing antimicrobial therapy

SR Andrews, TT Timbrook, MA Fisher… - Microbiology …, 2024 - Am Soc Microbiol
Extended-spectrum beta-lactamase (ESBL)-producing Enterobacterales bloodstream
infections (BSI) are associated with increased cost, morbidity, and mortality compared with …

[HTML][HTML] Optimization of Empirical Antimicrobial Therapy in Enterobacterales Bloodstream Infection Using the Extended-Spectrum Beta-Lactamase Prediction Score

BJ Haimerl, R Encinas, JA Justo, J Kohn… - Antibiotics, 2023 - mdpi.com
Clinical tools for the prediction of antimicrobial resistance have been derived and validated
without examination of their implementation in clinical practice. This study examined the …

Clinical Impact of Ceftriaxone Resistance in Escherichia coli Bloodstream Infections: A Multicenter Prospective Cohort Study

PD Tamma, L Komarow, L Ge… - Open forum …, 2022 - academic.oup.com
Abstract Background Ceftriaxone-resistant (CRO-R) Escherichia coli bloodstream infections
(BSIs) are common. Methods This is a prospective cohort of patients with E coli BSI at 14 …

[HTML][HTML] Clinical syndromes and treatment location predict utility of carbapenem sparing therapies in ceftriaxone-non-susceptible Escherichia coli bloodstream …

O Xie, K Cisera, L Taylor, C Hughes… - Annals of clinical …, 2020 - Springer
Background Cefiderocol, ceftazidime-avibactam, ceftolozane-tazobactam, intravenous
fosfomycin and plazomicin represent potential carbapenem sparing agents for extended …

[HTML][HTML] Simple bedside score to optimize the time and the decision to initiate appropriate therapy for carbapenem-resistant Enterobacteriaceae

V Leibman, ET Martin, R Tal-Jasper, L Grin… - Annals of clinical …, 2015 - Springer
Background Epidemiological characteristics of patients with bloodstream infections (BSI)
due to extended-spectrum β-lactamase producing (ESBL) and carbapenem-resistant (CRE) …

[HTML][HTML] Antimicrobial susceptibility of strains of Enterobacteriaceae isolated from bloodstream infections using current CLSI and EUCAST breakpoints

G Blandino, S Mastrojeni, R Inturri, A Sciacca… - Health, 2014 - scirp.org
Understanding local susceptibility patterns is important when selecting antimicrobials for
initial empirical antibiotic-therapy of bloodstream infections. Because the determination of …

Scoping review of risk-scoring tools for early prediction of bloodstream infections caused by carbapenem-resistant Enterobacterales: do we really have a reliable risk …

AT Aslan, Y Ezure, PNA Harris… - JAC-Antimicrobial …, 2024 - academic.oup.com
Abstract Background Bloodstream infections (BSIs) caused by carbapenem-resistant
Enterobacterales (CRE) are a global health concern. Rapid identification of CRE may …

Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance …

PNA Harris, PA Tambyah, DC Lye, Y Mo, TH Lee… - Jama, 2018 - jamanetwork.com
Importance Extended-spectrum β-lactamases mediate resistance to third-generation
cephalosporins (eg, ceftriaxone) inEscherichia coliandKlebsiella pneumoniae. Significant …

Association of piperacillin/tazobactam MIC and mortality in a cohort of ceftriaxone-resistant Escherichia coli bloodstream infections treated with piperacillin …

E Rando, F Salvati, F Sangiorgi… - Journal of …, 2024 - academic.oup.com
Objectives To assess the impact of piperacillin/tazobactam MICs on in-hospital 30 day
mortality in patients with third-generation cephalosporin-resistant Escherichia coli …