Insufficient dietary biotin intake, biotinidase deficiency, drug-biotin interactions can cause
biotin deficiency which may result in central nervous system dysfunctions. We hypothesized …

Biotin is a water-soluble vitamin that functions as a cofactor for biotin-dependent
carboxylases. The biochemical and physiological roles of biotin in brain regions have not yet …

Vitamin B (Vit B) plays a regulatory role in cognitive memory and learning. We examined the
biochemical and behavioral effects of biotin supplementation (BS) and swimming training …

To investigate the influence of intestinal flora upon the effects of biotin deficiency, we
provided germ-free and conventional mice with a purified biotin-deficient diet without egg …

To determine the effects of excess biotin administration on growth and water-soluble vitamin
metabolism, weaning rats were fed on a 20% casein diet containing 0.00002% biotin, or …

OBJECTIVE: The purpose of this investigation was to determine the effects of biotin
deficiency on maternal metabolism and embryonic development in pregnant mouse dams …

Biotin deficiency (Bt-D) is usually studied at the point at which the animal model exhibits the
signs of full-blown deficiency symptoms; in rats, this typically occurs at 6–8weeks of feeding …

Objectives This study aimed to investigate the protective effect of rutin against trimethyltin-
induced spatial learning and memory impairment in mice. This study focused on the role of …

Pregnant mice were fed a basal diet that not only did not contain biotin, but also contained
the spray‐dried egg white including avidin that caused the biotin deficiency. The effects of …

The effects of maternal dietary biotin deficiency on hamster embryos were examined by
adding different amounts of avidin (0, 10, 50, 100 or 1000 mg/kg diet) to a semipurified …