Divergent, Coexisting Pseudomonas aeruginosa Lineages in Chronic Cystic Fibrosis Lung Infections
D Williams, B Evans, S Haldenby… - American journal of …, 2015 - atsjournals.org
Rationale: Pseudomonas aeruginosa, the predominant cause of chronic airway infections of
patients with cystic fibrosis, exhibits extensive phenotypic diversity among isolates within …
patients with cystic fibrosis, exhibits extensive phenotypic diversity among isolates within …
Pseudomonas aeruginosa Population Diversity and Turnover in Cystic Fibrosis Chronic Infections
E Mowat, S Paterson, JL Fothergill… - American journal of …, 2011 - atsjournals.org
Rationale: Pseudomonas aeruginosa isolates from chronic cystic fibrosis lung infections
display multiple phenotypes indicating extensive population diversity. Objectives: We aimed …
display multiple phenotypes indicating extensive population diversity. Objectives: We aimed …
Genomic variation among contemporary Pseudomonas aeruginosa isolates from chronically infected cystic fibrosis patients
JCS Chung, J Becq, L Fraser… - Journal of …, 2012 - Am Soc Microbiol
The airways of individuals with cystic fibrosis (CF) often become chronically infected with
unique strains of the opportunistic pathogen Pseudomonas aeruginosa. Several lines of …
unique strains of the opportunistic pathogen Pseudomonas aeruginosa. Several lines of …
Long-Term Microevolution of Pseudomonas aeruginosa Differs between Mildly and Severely Affected Cystic Fibrosis Lungs
J Klockgether, N Cramer, S Fischer… - American journal of …, 2018 - atsjournals.org
Chronic airway infections with Pseudomonas aeruginosa determine morbidity in most
individuals with cystic fibrosis (CF). P. aeruginosa may persist for decades in CF lungs …
individuals with cystic fibrosis (CF). P. aeruginosa may persist for decades in CF lungs …
Evolutionary genomics of epidemic and nonepidemic strains of Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen of humans and is a major cause of
morbidity and mortality in patients with cystic fibrosis (CF). Prolonged infection of the …
morbidity and mortality in patients with cystic fibrosis (CF). Prolonged infection of the …
Pseudomonas aeruginosa adaptation and evolution in patients with cystic fibrosis
Intense genome sequencing of Pseudomonas aeruginosa isolates from cystic fibrosis (CF)
airways has shown inefficient eradication of the infecting bacteria, as well as previously …
airways has shown inefficient eradication of the infecting bacteria, as well as previously …
Evolutionary Genomics of Niche-Specific Adaptation to the Cystic Fibrosis Lung in Pseudomonas aeruginosa
JR Dettman, R Kassen - Molecular biology and evolution, 2021 - academic.oup.com
The comparative genomics of the transition of the opportunistic pathogen Pseudomonas
aeruginosa from a free-living environmental strain to one that causes chronic infection in the …
aeruginosa from a free-living environmental strain to one that causes chronic infection in the …
[HTML][HTML] Pseudomonas aeruginosa evolutionary adaptation and diversification in cystic fibrosis chronic lung infections
Pseudomonas aeruginosa populations undergo a characteristic evolutionary adaptation
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …
during chronic infection of the cystic fibrosis (CF) lung, including reduced production of …
[HTML][HTML] Genome evolution drives transcriptomic and phenotypic adaptation in Pseudomonas aeruginosa during 20 years of infection
SJT Wardell, J Gauthier, LW Martin… - Microbial …, 2021 - microbiologyresearch.org
The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lungs of
patients with cystic fibrosis (CF). During infection the bacteria evolve and adapt to the lung …
patients with cystic fibrosis (CF). During infection the bacteria evolve and adapt to the lung …
[HTML][HTML] Phenotypic Heterogeneity of Pseudomonas aeruginosa Populations in a Cystic Fibrosis Patient
ML Workentine, CD Sibley, B Glezerson, S Purighalla… - PloS one, 2013 - journals.plos.org
The opportunistic pathogen Pseudomonas aeruginosa chronically infects the lower airways
of patients with cystic fibrosis. Throughout the course of infection this organism undergoes …
of patients with cystic fibrosis. Throughout the course of infection this organism undergoes …