Background Pseudomonas aeruginosa cells are present as biofilms in the paranasal
sinuses and the lungs of chronically infected cystic fibrosis (CF) patients. Since different …

Emergence of epidemic clones and antibiotic resistance development compromises the
management of Pseudomonas aeruginosa cystic fibrosis (CF) chronic respiratory infections …

The opportunistic pathogen Pseudomonas aeruginosa is able to thrive in diverse ecological
niches and to cause serious human infection. P. aeruginosa environmental strains are …

Chronic respiratory infection by Pseudomonas aeruginosa contributessignificantly to the
morbidity and mortality associated with cystic fibrosis (CF). Using a series of phenotypic and …

Pseudomonas aeruginosa is the most prevalent pathogen of cystic fibrosis (CF) lung
disease. Its long persistence in CF airways is associated with sophisticated mechanisms of …

Background Pseudomonas aeruginosa populations within the cystic fibrosis lung exhibit
extensive phenotypic and genetic diversification. The resultant population diversity is …

Pseudomonas aeruginosa is a major opportunistic pathogen in cystic fibrosis (CF) patients
and causes a wide range of infections among other susceptible populations. Its inherent …

Clones C and PA14 are the worldwide most abundant clonal complexes in the
Pseudomonas aeruginosa population. The microevolution of clones C and PA14 was …

Pseudomonas aeruginosa is the leading pathogen of chronic cystic fibrosis (CF) lung
infection. Life-long persistance of P. aeruginosa in the CF lung requires a sophisticated …

Little is known about how within-host evolution compares between genotypically different
strains of the same pathogenic species. We sequenced the whole genomes of 474 …