Ultraviolet radiation–induced injury, chemokines, and leukocyte recruitment: an amplification cycle triggering cutaneous lupus erythematosus

S Meller, F Winterberg, M Gilliet, A Müller… - Arthritis & …, 2005 - Wiley Online Library
Objective To investigate the activation and recruitment pathways of relevant leukocyte
subsets during the initiation and amplification of cutaneous lupus erythematosus (LE) …

Pathogenesis of cutaneous lupus erythematosus

A Kuhn, M Bijl - Lupus, 2008 - journals.sagepub.com
Although for decades sunlight was suspected to be involved in the development of
cutaneous lupus erythematosus (CLE), only in recent years research on the effects of …

The role of cytokines in the pathogenesis of cutaneous lupus erythematosus

ES Robinson, VP Werth - Cytokine, 2015 - Elsevier
Cutaneous lupus erythematosus (CLE) is an inflammatory disease with a broad range of
cutaneous manifestations that may be accompanied by systemic symptoms. The …

Mechanisms involved in ultraviolet light‐induced immunosuppression

F Aubin - European journal of dermatology, 2003 - jle.com
Ultraviolet radiation (UV) represents one of the most important environmental factors
affecting human health, especially with regard to its hazardous effects on the generation of …

Ultraviolet B irradiation causes stimulator of interferon genes–dependent production of protective type I interferon in mouse skin by recruited inflammatory monocytes

C Sontheimer, D Liggitt, KB Elkon - Arthritis & Rheumatology, 2017 - Wiley Online Library
Objective Photosensitivity is common in patients with systemic lupus erythematosus,
although the mechanisms linking ultraviolet (UV) light to flares are not well understood. We …

[HTML][HTML] Role of the chemokine receptor CCR4 and its ligand thymus-and activation-regulated chemokine/CCL17 for lymphocyte recruitment in cutaneous lupus …

J Wenzel, S Henze, E Wörenkämper… - Journal of investigative …, 2005 - Elsevier
Skin-infiltrating T lymphocytes are thought to play a major role in the pathogenesis of
cutaneous lupus erythematosus (CLE). In this study, we investigated the role of the …

Ultraviolet light protection by a sunscreen prevents interferon‐driven skin inflammation in cutaneous lupus erythematosus

S Zahn, M Graef, N Patsinakidis… - Experimental …, 2014 - Wiley Online Library
Irradiation with ultraviolet (UV) light is an important exacerbating factor in cutaneous lupus
erythematosus (CLE) and induces various effects in the skin of patients with the disease …

Accumulation of apoptotic cells in the epidermis of patients with cutaneous lupus erythematosus after ultraviolet irradiation

A Kuhn, M Herrmann, S Kleber… - Arthritis & …, 2006 - Wiley Online Library
Objective To examine whether apoptosis contributes to the pathogenesis of skin lesions in
patients with cutaneous lupus erythematosus (CLE) after ultraviolet (UV) irradiation …

Type I interferons are involved in the development of ultraviolet B-induced inflammatory skin lesions in systemic lupus erythaematosus patients

E Reefman, H Kuiper, PC Limburg… - Annals of the …, 2008 - ard.bmj.com
Objective: To investigate the involvement of type I interferons and endothelial cell adhesion
molecules in the development of ultraviolet B (UVB)-induced systemic lupus erythaematosus …

Identification of type I interferon‐associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches

J Wenzel, T Tüting - Experimental dermatology, 2007 - Wiley Online Library
Cutaneous lupus erythematosus (CLE) is one of the most common dermatological
autoimmune disorders worldwide. Recently, several studies provided evidence for a …