Effects of In Utero PFOS Exposure on Epigenetics and Metabolism in Mouse Fetal Livers

TC Ho, HT Wan, WK Lee, TKY Lam, X Lin… - Environmental …, 2023 - ACS Publications
Prenatal exposure to perfluorooctanesulfonate (PFOS) increases fetus' metabolic risk;
however, the investigation of the underlying mechanism is limited. In this study, pregnant …

Transcriptome sequencing reveals prenatal PFOS exposure on liver disorders

KP Lai, JW Li, A Cheung, R Li, MB Billah, TF Chan… - Environmental …, 2017 - Elsevier
Perfluorooctane sulfonate (PFOS), a hepatic toxicant and a potential hepatocarcinogen, is
commonly used in industrial products. The widespread contamination of PFOS in human …

Effect of prenatal PFOS exposure on liver cell function in neonatal mice

X Liang, G Xie, X Wu, M Su, B Yang - Environmental Science and …, 2019 - Springer
Perfluorooctane sulfonate (PFOS), a hepatotoxic pollutant, is detected in the human cord
blood, and it may induce health risk to an embryo. In this study, we established intrauterine …

[HTML][HTML] Metabolic perturbations in pregnant rats exposed to low-dose perfluorooctanesulfonic acid: An integrated multi-omics analysis

G Yu, J Wang, Y Liu, T Luo, X Meng, R Zhang… - Environment …, 2023 - Elsevier
Emerging epidemiological evidence has linked per-and polyfluoroalkyl substances (PFAS)
exposure could be linked to the disturbance of gestational glucolipid metabolism, but the …

Perfluorooctane sulfonate-induced changes in fetal rat liver gene expression

JA Bjork, C Lau, SC Chang, JL Butenhoff, KB Wallace - Toxicology, 2008 - Elsevier
In utero exposure of laboratory rats to perfluorooctane sulfonate (PFOS, C8F17SO3−), a
chemically stable surfactant that is widely disseminated in the environment and present in …

In utero perfluorooctane sulfonate exposure causes low body weights of fetal rats: A mechanism study

X Li, L Ye, Y Ge, K Yuan, Y Zhang, Y Liang, J Wei… - Placenta, 2016 - Elsevier
Objectives The objective of the present study is to investigate the mechanism of
perfluorooctane sulfonate-induced low body weight of fetus by analysis of glucocorticoid …

Prenatal exposure to the contaminant perfluorooctane sulfonate elevates lipid peroxidation during mouse fetal development but not in the pregnant dam

YY Lee, CKC Wong, C Oger, T Durand… - Free radical …, 2015 - Taylor & Francis
Perfluorooctane sulfonate (PFOS), a member of the perfluorinated chemical family, has been
convincingly demonstrated to affect lipid metabolism in animals and humans and readily …

Effects of In Utero Exposure to Perfluorooctane Sulfonate on Placental Functions

HT Wan, AYM Wong, S Feng… - Environmental Science & …, 2020 - ACS Publications
Perfluorooctane sulfonate (PFOS) is a metabolic-disrupting chemical. There is a strong
association between maternal and cord blood PFOS concentrations, affecting metabolism in …

Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat …

X Meng, G Yu, T Luo, R Zhang, J Zhang, Y Liu - Chemosphere, 2023 - Elsevier
Emerging epidemiological evidence indicates potential associations between gestational
perfluorobutane sulfonate (PFBS) exposure and adverse metabolic outcomes in offspring …

Gene expression profiling in the liver and lung of perfluorooctane sulfonate-exposed mouse fetuses: comparison to changes induced by exposure to perfluorooctanoic …

MB Rosen, JE Schmid, KP Das, CR Wood… - Reproductive …, 2009 - Elsevier
Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are environmental
contaminants found in the tissues of humans and wildlife. They are activators of peroxisome …