Cellular mechanisms and behavioral outcomes in blast-induced neurotrauma: comparing experimental setups

ZS Bailey, WB Hubbard, PJ VandeVord - Injury Models of the Central …, 2016 - Springer
Blast-induced neurotrauma (BINT) has increased in incidence over the past decades and
can result in cognitive issues that have debilitating consequences. The exact primary and …

Twenty Years of Blast-Induced Neurotrauma: Current State of Knowledge

T Sachdeva, SG Ganpule - Neurotrauma Reports, 2024 - liebertpub.com
Blast-induced neurotrauma (BINT) is an important injury paradigm of neurotrauma research.
This short communication summarizes the current knowledge of BINT. We divide the BINT …

[HTML][HTML] Experimental animal models for studies on the mechanisms of blast-induced neurotrauma

M Risling, J Davidsson - Frontiers in neurology, 2012 - frontiersin.org
A blast injury is a complex type of physical trauma resulting from the detonation of explosive
compounds and has become an important issue due to the use of improvised explosive …

Novel model to investigate blast injury in the central nervous system

S Connell, J Gao, J Chen, R Shi - Journal of neurotrauma, 2011 - liebertpub.com
Blast-induced neurotrauma (BINT) is a common injury modality associated with the current
war efforts and increasing levels of terrorist activity. Exposure to the primary blast wave …

In vitro studies of primary explosive blast loading on neurons

NE Zander, T Piehler, ME Boggs… - Journal of …, 2015 - Wiley Online Library
In a military setting, traumatic brain injury (TBI) is frequently caused by blast waves that can
trigger a series of neuronal biochemical changes. Although many animal models have been …

[HTML][HTML] Blast injuries and blast-induced neurotrauma: overview of pathophysiology and experimental knowledge models and findings

I Cernak - 2015 - europepmc.org
Explosions are physical phenomena that result in the sudden release of energy; they may
be chemical, nuclear, or mechanical. This process results in a near-instantaneous pressure …

The pathobiology of blast injuries and blast-induced neurotrauma as identified using a new experimental model of injury in mice

I Cernak, AC Merkle, VE Koliatsos, JM Bilik… - Neurobiology of …, 2011 - Elsevier
Current experimental models of blast injuries used to study blast-induced neurotrauma
(BINT) vary widely, which makes the comparison of the experimental results extremely …

[HTML][HTML] A Multiscale Approach to Blast Neurotrauma Modeling: Part II: Methodology for Inducing Blast Injury to in vitro Models

GB Effgen, CD Hue, E Vogel III, MB Panzer… - Frontiers in …, 2012 - frontiersin.org
Due to the prominent role of improvised explosive devices (IEDs) in wounding patterns of
US war-fighters in Iraq and Afghanistan, blast injury has risen to a new level of importance …

[PDF][PDF] Blast related neurotrauma: a review of cellular injury

LY Leung, PJ VandeVord, AL Dal Cengio… - Molecular & cellular …, 2008 - cdn.techscience.cn
Historically, blast overpressure is known to affect primarily gas-containing organs such as
the lung and ear. More recent interests focus on its ability to cause damage to solid organs …

[HTML][HTML] Acute Pathophysiology of Blast Injury—From Biomechanics to Experiments and Computations

N Chandra, A Sundaramurthy - Brain neurotrauma: Molecular …, 2015 - ncbi.nlm.nih.gov
Traumatic brain injury (TBI) has been a major public health concern in the United States for
decades; with an average of 1.4 million sustaining TBI, leading to 50,000 deaths, 235,000 …