Hepatitis B virus persistence and reactivation

Y Shi, M Zheng - bmj, 2020 - bmj.com
Hepatitis B virus (HBV) infection causes chronic hepatitis and has long term complications.
Individuals ever infected with HBV are at risk of viral reactivation under certain …

[PDF][PDF] Natural history of chronic hepatitis B virus infection: what we knew in 1981 and what we know in 2005

HJ Yim, ASF Lok - Hepatology, 2006 - Wiley Online Library
Remarkable progress has been made in our understanding of the natural history of chronic
hepatitis B virus (HBV) infection in the past 25 years. Availability of sensitive HBV DNA …

Viral hepatitis B: clinical and epidemiological characteristics

GS Burns, AJ Thompson - Cold Spring …, 2014 - perspectivesinmedicine.cshlp.org
It is now 50 years since the discovery of the hepatitis B virus (HBV), and, despite the
availability of a prophylactic vaccine for more than 20 years, HBV infection remains a …

Natural history of chronic hepatitis B

BJ McMahon - Clinics in liver disease, 2010 - liver.theclinics.com
Hepatitis B virus (HBV) is the cause of one of the most common chronic viral infections in the
world. More than 2 billion persons have been exposed to HBV and 350 to 400 million …

Mechanisms of hepatitis B virus persistence

KN Tsai, CF Kuo, JHJ Ou - Trends in microbiology, 2018 - cell.com
Hepatitis B virus (HBV) chronically infects 250 million people worldwide, resulting in nearly
one million deaths annually. Studies in recent years have significantly improved our …

[PDF][PDF] Persistent hepatitis B virus infection in subjects without hepatitis B surface antigen: clinically significant or purely “occult”?

C Bréchot, V Thiers, D Kremsdorf, B Nalpas, S Pol… - …, 2001 - Wiley Online Library
Studies based on serologic assays for hepatitis B virus (HBV) have led to the concept that
HBV is eliminated after the resolution of an acute infection, although a chronic carrier state …

[HTML][HTML] Natural history of chronic hepatitis B: phases in a complex relationship

CMN Croagh, JS Lubel - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Chronic hepatitis B (CHB) is a condition of global prevalence and its sequelae include
cirrhosis and hepatocellular carcinoma. The natural history of CHB is a complex interplay of …

Persistent infection of humans with hepatitis B virus: mechanisms and consequences

D Ganem - Reviews of infectious diseases, 1982 - academic.oup.com
Although most infections of humans with hepatitis B virus are self-limited, up to 10% of
individuals experiencing primary infection remain persistently infected. These individuals …

Hepatitis B infection: current concepts and future challenges

G Nebbia, D Peppa, MK Maini - QJM: An International Journal of …, 2012 - academic.oup.com
Chronic hepatitis B (CHB) is a global health problem affecting more than 350 million people
worldwide. Chronic carriage of HBV is related to the age when the infection occurs; the …

Natural history of chronic hepatitis B virus infection and long‐term outcome under treatment

YF Liaw - Liver international, 2009 - Wiley Online Library
Chronic hepatitis B virus (HBV) infection is a dynamic state of interactions among HBV, the
hepatocytes and the immune system of the patient. Perinatally or early childhood‐acquired …