Aquaporin-1 and aquaporin-4 expression in ependyma, choroid plexus and surrounding transition zones in the human brain

R Bihlmaier, F Deffner, U Mattheus, PH Neckel, B Hirt… - Biomolecules, 2023 - mdpi.com
The choroid plexus (CP) is a structure in the brain ventricles that produces the main part of
the cerebrospinal fluid (CSF). It is covered with specialized cells which show epithelial …

Aquaporin-4 expression in the human choroid plexus

F Deffner, C Gleiser, U Mattheus, A Wagner… - Cellular and Molecular …, 2022 - Springer
The choroid plexus (CP) consists of specialized ependymal cells and underlying blood
vessels and stroma producing the bulk of the cerebrospinal fluid (CSF). CP epithelial cells …

Shifting from ependyma to choroid plexus epithelium and the changing expressions of aquaporin‐1 and aquaporin‐4

AF Mack, R Bihlmaier, F Deffner - The Journal of Physiology, 2023 - Wiley Online Library
The cells of the choroid plexus (CP) epithelium are specialized ependymal cells (ECs) but
have distinct properties. The CP cells and ECs form single‐cell sheets contiguous to each …

Choroid plexus and aquaporin-1: a novel explanation of cerebrospinal fluid production

PL Longatti, L Basaldella, E Orvieto, A Fiorindi… - Pediatric …, 2004 - karger.com
Aquaporins are selective water channel proteins that play a central role in the homeostasis
of human body water. The choroid plexus (CP) is considered to be the main cerebrospinal …

Deletion of aquaporin‐4 changes the perivascular glial protein scaffold without disrupting the brain endothelial barrier

M Eilert‐Olsen, NN Haj‐Yasein, GF Vindedal, R Enger… - Glia, 2012 - Wiley Online Library
Expression of the water channel aquaporin‐4 (AQP4) at the blood–brain interface is
dependent upon the dystrophin associated protein complex. Here we investigated whether …

Anchoring of aquaporin-4 in brain: molecular mechanisms and implications for the physiology and pathophysiology of water transport

M Amiry-Moghaddam, DS Frydenlund, OP Ottersen - Neuroscience, 2004 - Elsevier
Astrocytes show an enrichment of aquaporin-4 (AQP4) in those parts of the plasma
membrane that are apposed to pial or perivascular basal laminae. This observation begged …

Differences in distribution and regulation of astrocytic aquaporin‐4 in human and rat hydrocephalic brain

AD Skjolding, AV Holst, H Broholm… - Neuropathology and …, 2013 - Wiley Online Library
AD Skjolding, AV Holst, H. Broholm, H. Laursen and M. Juhler (2013) Neuropathology and
Applied Neurobiology39, 179–191 Differences in distribution and regulation of astrocytic …

[HTML][HTML] Expression of aquaporins in the rat choroid plexus

Z Nazari, M Nabiuni, ZS Nejad, B Delfan… - Archives of …, 2015 - brieflands.com
Background: Aquaporins (AQPs) are water channels that play a key role in water transport in
many epithelia. Recent studies have shown that AQP1, located in the apical membrane of …

[HTML][HTML] Expression of aquaporin 1 and aquaporin 4 water channels in rat choroid plexus

T Speake, LJ Freeman, PD Brown - Biochimica et Biophysica Acta (BBA) …, 2003 - Elsevier
The role of aquaporins in cerebrospinal fluid (CSF) secretion was investigated in this study.
Western analysis and immunocytochemistry were used to examine the expression of …

Evidence that pericytes regulate aquaporin-4 polarization in mouse cortical astrocytes

GA Gundersen, GF Vindedal, Ø Skare… - Brain Structure and …, 2014 - Springer
Abstract Aquaporin-4 (AQP4) water channels are concentrated in astrocytic endfoot
membranes at the brain–blood and brain–cerebrospinal fluid interfaces. The mechanisms …