Purpose Many studies have shown that cytochrome P450 (CYP) gene polymorphisms are
usually associated with an increased risk of cardiovascular and cerebrovascular diseases …

Objective: The present study aims to investigate the relationship between CYP2J2 gene
polymorphisms and ischemic stroke (IS) in a Chinese Han population. Methods: We …

Background and purpose: Ischemic stroke (IS) is the main cause of mortality and disability
among the old people in China and is a multifactorial disease influenced by many factors …

Abstract Background Cytochrome P450 (CYP) 2C19 is a very important drug metabolizing
enzyme. Although the single nucleotide polymorphisms (SNPs) of CYP2C19 G681A and …

Aim: Ischemic stroke (IS) is a multifactorial disease caused by environmental risk factors and
genetic susceptibility. However, few studies have assessed whether gene–gene interactions …

Introduction: Ischemic stroke (IS) is an extremely complex disease caused by the combined
action of multiple environmental and genetic factors. CYP1B1 is a member of the …

Background Ischemic stroke (IS) is a serious cardiovascular disease and is associated with
several single nucleotide polymorphisms (SNPs). However, the role of Cytochrome P450 …

Background CYP4 subfamily V member 2 (CYP4V2) polymorphisms are related to venous
thromboembolism. However, the influence of CYP4V2 polymorphisms on the susceptibility …

Objective To investigate the correlation between CYP2C19 gene polymorphism and elderly
cerebral infarction. Methods Two polymorphisms including rs4244285 and rs4986893 of the …

Objective The renin–angiotensin–aldosterone system isimportant for cerebrovascular
research because it influences blood pressure, vasoconstriction, thrombosis, and vessel …