[HTML][HTML] Impaired autophagy in amyloid-beta pathology: A traditional review of recent Alzheimer's research
M Yuan, Y Wang, Z Huang, F Jing, P Qiao… - Journal of Biomedical …, 2023 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most prevalent neurodegenerative disorder. The major
pathological changes in AD progression are the generation and accumulation of amyloid …
pathological changes in AD progression are the generation and accumulation of amyloid …
Autophagy: a double-edged sword in Alzheimer's disease
YT Tung, BJ Wang, MK Hu, WM Hsu, H Lee… - Journal of …, 2012 - Springer
Autophagy is a major protein degradation pathway that is essential for stress-induced and
constitutive protein turnover. Accumulated evidence has demonstrated that amyloid-β (Aβ) …
constitutive protein turnover. Accumulated evidence has demonstrated that amyloid-β (Aβ) …
Dual roles for autophagy: degradation and secretion of Alzheimer's disease Aβ peptide
P Nilsson, TC Saido - Bioessays, 2014 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disease exhibiting amyloid beta (Aβ)
peptide accumulation as a key characteristic. Autophagy, which is dysregulated in AD …
peptide accumulation as a key characteristic. Autophagy, which is dysregulated in AD …
Autophagy dysfunction in Alzheimer's disease
L Li, X Zhang, W Le - Neurodegenerative Diseases, 2010 - karger.com
Autophagy is a lysosome degradation pathway that turns over cytoplasmic materials and
helps the cell to maintain homeostasis. Usually, it is activated under conditions of nutrient …
helps the cell to maintain homeostasis. Usually, it is activated under conditions of nutrient …
Autophagy and Alzheimer's disease: from molecular mechanisms to therapeutic implications
MS Uddin, A Stachowiak, AA Mamun… - Frontiers in aging …, 2018 - frontiersin.org
Alzheimer's disease (AD) is the most common cause of progressive dementia in the elderly.
It is characterized by a progressive and irreversible loss of cognitive abilities and formation …
It is characterized by a progressive and irreversible loss of cognitive abilities and formation …
[HTML][HTML] Autophagy in Alzheimer's disease pathogenesis: Therapeutic potential and future perspectives
Alzheimer's disease (AD) is a complex neurodegenerative disease in the elderly and the
most common cause of human dementia. AD is characterized by accumulation of abnormal …
most common cause of human dementia. AD is characterized by accumulation of abnormal …
New insights into autophagy dysfunction related to amyloid beta toxicity and neuropathology in Alzheimer's disease
The fine control of neuronal proteostasis is an essential element that preserves cell viability.
Advancing age is a major risk factor for Alzheimer's disease (AD), and autophagy is thought …
Advancing age is a major risk factor for Alzheimer's disease (AD), and autophagy is thought …
Molecular mechanism of autophagy: Its role in the therapy of Alzheimer's disease
Y Zhao, Y Zhang, J Zhang, X Zhang… - Current …, 2020 - ingentaconnect.com
Alzheimer's disease (AD) is a neurodegenerative disorder of progressive dementia that is
characterized by the accumulation of beta-amyloid (Aβ)-containing neuritic plaques and …
characterized by the accumulation of beta-amyloid (Aβ)-containing neuritic plaques and …
Proteostasis and neurodegeneration: a closer look at autophagy in Alzheimer's disease
H Barmaki, A Nourazarian… - Frontiers in Aging …, 2023 - frontiersin.org
Alzheimer's disease (AD) is characterized by the accumulation of misfolded amyloid-beta
and tau proteins. Autophagy acts as a proteostasis process to remove protein clumps …
and tau proteins. Autophagy acts as a proteostasis process to remove protein clumps …
The implications of autophagy in Alzheimer's disease
T Hamano, K Hayashi, N Shirafuji… - Current Alzheimer …, 2018 - ingentaconnect.com
The pathogenic mechanisms of Alzheimer's Disease (AD) involve the deposition of
abnormally misfolded proteins, amyloid β protein (Aβ) and tau protein. Aβ comprises senile …
abnormally misfolded proteins, amyloid β protein (Aβ) and tau protein. Aβ comprises senile …