The use of molecular markers of resistance to monitor the emergence, and the spread of
parasite resistance to antimalarial drugs is a very effective way of monitoring antimalarial …

Background Prior to this project, only a handful of online visualizations existed for exploring
the published literature on molecular markers of antimalarial drug resistance, and none …

The identification of parasite molecular markers involved in resistance to antimalarial
compounds is of great interest for monitoring the development and spread of resistance in …

Drug resistance in Plasmodium falciparum compromises the effectiveness of antimalarial
therapy. This study aimed to evaluate the extent of drug resistance in parasites obtained …

Background Pfcrt gene has been associated with chloroquine resistance and the pfmdr1
gene can alter malaria parasite susceptibility to lumefantrine, mefloquine, and chloroquine …

Plasmodium falciparum response mechanisms to the major artemisinin-based combination
therapies (ACTs) are largely unknown. Multidrug-resistance protein (MRP)–like adenosine …

Background To assess the effect on malaria prevalence, village specific monthly
administrations of pyrimethamine, chlorproguanil, chloroquine or placebo were given to …

Abstract Background Drug resistance in Plasmodium falciparum is a major problem in
malaria control especially along the Thai-Myanmar and Thai-Cambodia borders. To date, a …

Stepwise selection for increased mefloquine resistance in a line of Plasmodium falciparum
in vitro resulted in increased resistance to halofantrine and quinine, increased sensitivity to …

Resistance to quinoline antimalarial drugs has emerged in different parts of the world and
involves sets of discrete mutational changes in pfcrt and pfmdr1 in the human malaria …