Monogenic forms of heritable kidney disease account for a significant proportion of chronic
kidney disease (CKD) across both pediatric and adult patient populations and up to 11% of …

Abstract Purpose of Review To provide a comprehensive update on the role of genetic
testing for the evaluation of kidney transplant recipient and living donor candidates. Recent …

New evidence indicates potential benefit of genomics to illuminate nonkidney monogenic
morbidity and mortality risk among kidney transplant recipients. This might be of direct …

Genomic medicine has been revolutionizing our approach to health problems and disease
pathophysiology. Increasing evidence suggests that inherited kidney disorders (IKD) …

Genetic testing may have broad benefits for patients and their families. Knowing the precise
molecular etiology of disease can help clinicians determine the exact therapeutic course …

As much as 16-17% European and American patients on renal replacement therapy do not
have a conclusive diagnosis of the cause of their renal failure. This may have important …

Growth in knowledge of the genetics of kidney disease has revealed that significant
percentages of patients with diverse types of nephropathy have causative mutations …

Genetic testing is increasingly used in the workup and diagnosis of kidney disease and
kidney-related disorders of undetermined cause. Out-of-pocket costs for clinical genetic …

Background Genetic kidney disease is well established as an important cause of pediatric
kidney failure, and genetic testing might increase diagnostic accuracy, but evidence is …

Background. Recent studies identified underlying genetic causes in a proportion of patients
with various forms of kidney disease. In particular, genetic testing reclassified some focal …