Cyclin A1 is a promising antigen for T cell therapy being selectively expressed in high-grade
ovarian cancer (OC) and acute myeloid leukemia (AML) stem cells. For adoptive T cell …

We eluted peptides from class I molecules of HLA-A2. 1+ breast adenocarcinoma and
loaded reverse phase high-performance liquid chromatography (HPLC) fractions onto …

With the aim to identify cyclin B1-derived peptides with high affinity for HLA-A2, we used
three in silico prediction algorithms to screen the protein sequence for possible HLA-A2 …

Cyclin A1-derived peptides recently gained new interest in a study by Ochsenreither et al.,
who characterized cyclin A1 as a promising antigen in acute myeloid leukemia (AML) due to …

Cyclin‐A2, a key cell cycle regulator, has been shown to be overexpressed in various types
of malignancies with little expression in normal tissue. Such tumor‐associated genes …

Purpose: Cyclin D1, a key cell cycle regulator, is overexpressed in multiple types of cancer.
Such tumor-associated genes may be useful targets for cancer immunotherapy …

Toward the development of a novel cancer immunotherapy, we have previously identified
several tumor‐associated antigens (TAAs) and the epitopes recognized by human …

Cyclin D1 is over-expressed in various human tumors and therefore can be a potential
oncogenic target antigen. However, only a limited number of T cell epitopes has been …

T‐helper (Th) cells play an important role in orchestrating the effector function of CTL in anti‐
tumor immunity. However, only a limited number of Th cell epitopes has been characterized …

Background Cyclin A1 is essential for male gametopoiesis. In acute myeloid leukemia, it acts
as a leukemia-associated antigen. Cyclin A1 expression has been reported in several …