Synthesis of Dendritic Cell-Targeted Polymeric Nanoparticles for Selective Delivery of mRNA Vaccines to Elicit Enhanced Immune Responses
CH Wong - bioRxiv, 2023 - biorxiv.org
Recent development of SARS-CoV-2 spike mRNA vaccines to control the pandemic is a
breakthrough in the field of vaccine development. mRNA vaccines are generally formulated …
breakthrough in the field of vaccine development. mRNA vaccines are generally formulated …
Synthesis of a dendritic cell-targeted self-assembled polymeric nanoparticle for selective delivery of mRNA vaccines to elicit enhanced immune responses
CY Fan, SW Wang, C Chung, JY Chen, CY Chang… - Chemical …, 2024 - pubs.rsc.org
Recent development of SARS-CoV-2 spike mRNA vaccines to control the pandemic is a
breakthrough in the field of vaccine development. mRNA vaccines are generally formulated …
breakthrough in the field of vaccine development. mRNA vaccines are generally formulated …
Synthesis and Assembly of mRNA-Bifunctional Lipid Nanoparticle (BLNP) for Selective Delivery of mRNA Vaccines to Dendritic Cells
CH Wong - bioRxiv, 2023 - biorxiv.org
The fight against COVID-19 pandemic has gained a strong consensus about the importance
of developing mRNA vaccines to rapidly respond to an outbreak. Several studies have …
of developing mRNA vaccines to rapidly respond to an outbreak. Several studies have …
An inoculation site-retained mRNA vaccine induces robust immune responses against SARS-CoV-2 variants
L Huang, F Zhao, M He, Y Fang, X Ma, S Lu, E Li… - Journal of Controlled …, 2024 - Elsevier
Abstract mRNA-based vaccines and therapeutic agents hold great promise in prevention
and treatment of human diseases, yet high percentage of systemic adverse effect in clinic …
and treatment of human diseases, yet high percentage of systemic adverse effect in clinic …
Straight to the point: targeted mRNA-delivery to immune cells for improved vaccine design
B Clemente, M Denis, CP Silveira, F Schiavetti… - Frontiers in …, 2023 - frontiersin.org
With the deepening of our understanding of adaptive immunity at the cellular and molecular
level, targeting antigens directly to immune cells has proven to be a successful strategy to …
level, targeting antigens directly to immune cells has proven to be a successful strategy to …
Enhanced immunogenicity induced by mRNA vaccines with various lipid nanoparticles as carriers for SARS-CoV-2 infection
Y Zhang, J Wang, H Xing, C Liu, W Zha… - Journal of Materials …, 2023 - pubs.rsc.org
mRNA vaccines have emerged as a highly promising approach for preventing cancer and
infectious diseases, attributed to their superior immunogenicity, rapid development speed …
infectious diseases, attributed to their superior immunogenicity, rapid development speed …
Dendritic Cell‐Mimicking Nanoparticles Promote mRNA Delivery to Lymphoid Organs
Y Cao, J Long, H Sun, Y Miao, Y Sang, H Lu… - Advanced …, 2023 - Wiley Online Library
Spleen and lymphoid organs are important targets for messenger RNA (mRNA) delivery in
various applications. Current nanoparticle delivery methods rely on drainage to lymph …
various applications. Current nanoparticle delivery methods rely on drainage to lymph …
[PDF][PDF] Nanomaterial delivery systems for mRNA vaccines. Vaccines 2021, 9, 65
MD Buschmann, MJ Carrasco, S Alishetty, M Paige… - 2021 - pdfs.semanticscholar.org
The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the
development of lipid nanoparticle delivery systems that not only efficiently express the …
development of lipid nanoparticle delivery systems that not only efficiently express the …
STING agonist-derived LNP-mRNA vaccine enhances protective immunity against SARS-CoV-2
Lipid nanoparticle (LNP)-mediated delivery of messenger RNA (mRNA) COVID-19 vaccines
has provided large-scale immune protection to the public. To elicit a robust immune …
has provided large-scale immune protection to the public. To elicit a robust immune …
Adjuvant lipidoid-substituted lipid nanoparticles augment the immunogenicity of SARS-CoV-2 mRNA vaccines
Lipid nanoparticle (LNP)-formulated messenger RNA (mRNA) vaccineare a promising
platform to prevent infectious diseases as demonstrated by the recent success of SARS-CoV …
platform to prevent infectious diseases as demonstrated by the recent success of SARS-CoV …
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