Recent development of SARS-CoV-2 spike mRNA vaccines to control the pandemic is a
breakthrough in the field of vaccine development. mRNA vaccines are generally formulated …

The fight against COVID-19 pandemic has gained a strong consensus about the importance
of developing mRNA vaccines to rapidly respond to an outbreak. Several studies have …

Abstract mRNA-based vaccines and therapeutic agents hold great promise in prevention
and treatment of human diseases, yet high percentage of systemic adverse effect in clinic …

With the deepening of our understanding of adaptive immunity at the cellular and molecular
level, targeting antigens directly to immune cells has proven to be a successful strategy to …

mRNA vaccines have emerged as a highly promising approach for preventing cancer and
infectious diseases, attributed to their superior immunogenicity, rapid development speed …

Spleen and lymphoid organs are important targets for messenger RNA (mRNA) delivery in
various applications. Current nanoparticle delivery methods rely on drainage to lymph …

The recent success of mRNA vaccines in SARS-CoV-2 clinical trials is in part due to the
development of lipid nanoparticle delivery systems that not only efficiently express the …

Lipid nanoparticle (LNP)-mediated delivery of messenger RNA (mRNA) COVID-19 vaccines
has provided large-scale immune protection to the public. To elicit a robust immune …

Lipid nanoparticles (LNPs) have recently emerged as one of the most advanced
technologies for the highly efficient in vivo delivery of exogenous mRNA, particularly for …

Lipid nanoparticle (LNP)-formulated messenger RNA (mRNA) vaccineare a promising
platform to prevent infectious diseases as demonstrated by the recent success of SARS-CoV …