An experimental protocol for fertility preservation in prepubertal boys recently diagnosed with cancer: a report of acceptability and safety

JP Ginsberg, CA Carlson, K Lin, WL Hobbie… - Human …, 2010 - academic.oup.com
BACKGROUND Gonadal damage is a consequence of therapy for pediatric malignancies.
Prepubertal males have no semen or mature spermatozoa, posing a challenge for fertility …

Testicular tissue cryopreservation in prepubertal male children: an analysis of parental decision‐making

JP Ginsberg, Y Li, CA Carlson, CR Gracia… - Pediatric blood & …, 2014 - Wiley Online Library
Background Infertility is an unfortunate treatment‐related consequence for some pediatric
malignancies as well as some non‐malignant conditions treated with stem cell transplant …

Histology of testicular biopsies obtained for experimental fertility preservation protocol in boys with cancer

EJ Pietzak, GE Tasian, SK Tasian, RL Brinster… - The Journal of …, 2015 - auajournals.org
Purpose: Cryopreservation of testicular tissue with subsequent reimplantation after therapy
has the potential to preserve fertility for prepubertal boys with cancer. We present the …

Testicular biopsy for fertility preservation in prepubertal boys with cancer: identifying preferences for procedure and reactions to disclosure practices

AA Gupta, RM Donen, L Sung, KM Boydell… - The Journal of …, 2016 - auajournals.org
Purpose: Fertility preservation options are limited in prepubertal boys with cancer.
Worldwide there has been growing interest in testicular tissue cryopreservation as a …

Development of the testis in pre-pubertal boys with cancer after biopsy for fertility preservation

M Uijldert, A Meißner, AA De Melker… - Human …, 2017 - academic.oup.com
STUDY QUESTION Is testicular growth affected by a testicular biopsy intended for fertility
preservation in pre-pubertal boys with cancer? SUMMARY ANSWER Testicular growth of …

Testicular biopsy in prepubertal boys: a worthwhile minor surgical procedure?

A Faure, A Bouty, M O'brien, J Thorup, J Hutson… - Nature Reviews …, 2016 - nature.com
No consensus exists regarding the precise role of testicular biopsy in prepubertal boys,
although it is considered useful for assessing the potential consequences of undescended …

A short report on current fertility preservation strategies for boys

WLC Ho, H Bourne, D Gook, G Clarke… - Clinical …, 2017 - Wiley Online Library
Background Advances in cancer treatment have led to improved long‐term survival after
childhood cancer, but often at a price of impaired future fertility. Fertility preservation (FP) in …

Methods of cryopreservation of testicular tissue with viable spermatogonia in pre-pubertal boys undergoing gonadotoxic cancer treatment

V Keros, K Hultenby, B Borgström… - Human …, 2007 - academic.oup.com
BACKGROUND Banking of testicular tissue from pre-pubertal boys before gonadotoxic
treatment is a crucial step in fertility preservation. We wanted to find optimal methods for …

Evaluation of ovarian and testicular tissue cryopreservation in children undergoing gonadotoxic therapies

SN Babayev, E Arslan, S Kogan, F Moy… - Journal of assisted …, 2013 - Springer
Objective Ovarian and testicular tissue cryopreservation are the only fertility preservation
options for sexually immature individuals. Because of their experimental nature, it is …

Testicular tissue cryopreservation in boys. Ethical and legal issues: case report

G Bahadur, R Chatterjee, D Ralph - Human Reproduction, 2000 - academic.oup.com
Sperm preservation prior to chemotherapy and radiotherapy is common practice in adult
males. Spermatozoa are usually retrieved from an ejaculated sample although there are …