Polyadenylation of mRNA in prokaryotes

N Sarkar - Annual review of biochemistry, 1997 - annualreviews.org
The 3′-ends of both prokaryotic and eukaryotic mRNA are polyadenylated, but the poly (A)
tracts of prokaryotic mRNA are generally shorter, ranging from 15 to 60 adenylate residues …

An atlas of plant full-length RNA reveals tissue-specific and monocots–dicots conserved regulation of poly (A) tail length

J Jia, W Lu, B Liu, H Fang, Y Yu, W Mo, H Zhang, X Jin… - Nature Plants, 2022 - nature.com
Poly (A) tail is a hallmark of eukaryotic messenger RNA and its length plays an essential role
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …

Retracted: Poly (A) polymerase-based poly (A) length assay

DP Patil, B Bakthavachalu, DR Schoenberg - … : methods and protocols, 2014 - Springer
Abstract mRNA polyadenylation functions in nuclear export, translation, and stability. We
describe an efficient protocol designed to assess poly (A) tail length that is based on 3 …

Signals for pre‐mRNA cleavage and polyadenylation

B Tian, JH Graber - Wiley interdisciplinary reviews: RNA, 2012 - Wiley Online Library
Pre‐mRNA cleavage and polyadenylation is an essential step for 3′ end formation of
almost all protein‐coding transcripts in eukaryotes. The reaction, involving cleavage of …

RNA stabilization by a poly (A) tail 3′-end binding pocket and other modes of poly (A)-RNA interaction

SF Torabi, AT Vaidya, KT Tycowski, SJ DeGregorio… - Science, 2021 - science.org
INTRODUCTION The polyadenylate [poly (A)] tail is one of the most conserved modifications
of RNA molecules and is an important contributor to RNA function. In conjunction with other …

PABPN1 shuts down alternative poly (A) sites

M Simonelig - Cell research, 2012 - nature.com
Although overlooked for many years, alternative cleavage and polyadenylation (APA) is now
emerging as a major mechanism of gene regulation. A recent study identifies poly (A) …

New ways to meet your (3′) end—oligouridylation as a step on the path to destruction

CJ Wilusz, J Wilusz - Genes & development, 2008 - genesdev.cshlp.org
Messenger RNA degradation is a vital contributor to the control of gene expression that
generally involves removal of a poly (A) tail in both prokaryotes and eukaryotes. In a thought …

Deadenylation: enzymes, regulation, and functional implications

YB Yan - Wiley Interdisciplinary Reviews: RNA, 2014 - Wiley Online Library
Lengths of the eukaryotic messenger RNA (mRNA) poly (A) tails are dynamically changed
by the opposing effects of poly (A) polymerases and deadenylases. Modulating poly (A) tail …

Detection and characterization of polyadenylated RNA in Eukarya, Bacteria, Archaea, and organelles

S Slomovic, V Portnoy, G Schuster - Methods in enzymology, 2008 - Elsevier
The posttranscriptional addition of poly (A) extensions to RNA is a phenomenon common to
almost all organisms. In eukaryotes, a stable poly (A) tail is added to the 3′‐end of most …

FLAM-seq: full-length mRNA sequencing reveals principles of poly (A) tail length control

I Legnini, J Alles, N Karaiskos, S Ayoub, N Rajewsky - Nature Methods, 2019 - nature.com
Although messenger RNAs are key molecules for understanding life, until now, no method
has existed to determine the full-length sequence of endogenous mRNAs including their …