Polyadenylation of mRNA in prokaryotes
N Sarkar - Annual review of biochemistry, 1997 - annualreviews.org
The 3′-ends of both prokaryotic and eukaryotic mRNA are polyadenylated, but the poly (A)
tracts of prokaryotic mRNA are generally shorter, ranging from 15 to 60 adenylate residues …
tracts of prokaryotic mRNA are generally shorter, ranging from 15 to 60 adenylate residues …
An atlas of plant full-length RNA reveals tissue-specific and monocots–dicots conserved regulation of poly (A) tail length
Poly (A) tail is a hallmark of eukaryotic messenger RNA and its length plays an essential role
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …
Retracted: Poly (A) polymerase-based poly (A) length assay
DP Patil, B Bakthavachalu, DR Schoenberg - … : methods and protocols, 2014 - Springer
Abstract mRNA polyadenylation functions in nuclear export, translation, and stability. We
describe an efficient protocol designed to assess poly (A) tail length that is based on 3 …
describe an efficient protocol designed to assess poly (A) tail length that is based on 3 …
Signals for pre‐mRNA cleavage and polyadenylation
Pre‐mRNA cleavage and polyadenylation is an essential step for 3′ end formation of
almost all protein‐coding transcripts in eukaryotes. The reaction, involving cleavage of …
almost all protein‐coding transcripts in eukaryotes. The reaction, involving cleavage of …
RNA stabilization by a poly (A) tail 3′-end binding pocket and other modes of poly (A)-RNA interaction
INTRODUCTION The polyadenylate [poly (A)] tail is one of the most conserved modifications
of RNA molecules and is an important contributor to RNA function. In conjunction with other …
of RNA molecules and is an important contributor to RNA function. In conjunction with other …
PABPN1 shuts down alternative poly (A) sites
M Simonelig - Cell research, 2012 - nature.com
Although overlooked for many years, alternative cleavage and polyadenylation (APA) is now
emerging as a major mechanism of gene regulation. A recent study identifies poly (A) …
emerging as a major mechanism of gene regulation. A recent study identifies poly (A) …
New ways to meet your (3′) end—oligouridylation as a step on the path to destruction
CJ Wilusz, J Wilusz - Genes & development, 2008 - genesdev.cshlp.org
Messenger RNA degradation is a vital contributor to the control of gene expression that
generally involves removal of a poly (A) tail in both prokaryotes and eukaryotes. In a thought …
generally involves removal of a poly (A) tail in both prokaryotes and eukaryotes. In a thought …
Deadenylation: enzymes, regulation, and functional implications
YB Yan - Wiley Interdisciplinary Reviews: RNA, 2014 - Wiley Online Library
Lengths of the eukaryotic messenger RNA (mRNA) poly (A) tails are dynamically changed
by the opposing effects of poly (A) polymerases and deadenylases. Modulating poly (A) tail …
by the opposing effects of poly (A) polymerases and deadenylases. Modulating poly (A) tail …
Detection and characterization of polyadenylated RNA in Eukarya, Bacteria, Archaea, and organelles
S Slomovic, V Portnoy, G Schuster - Methods in enzymology, 2008 - Elsevier
The posttranscriptional addition of poly (A) extensions to RNA is a phenomenon common to
almost all organisms. In eukaryotes, a stable poly (A) tail is added to the 3′‐end of most …
almost all organisms. In eukaryotes, a stable poly (A) tail is added to the 3′‐end of most …
FLAM-seq: full-length mRNA sequencing reveals principles of poly (A) tail length control
I Legnini, J Alles, N Karaiskos, S Ayoub, N Rajewsky - Nature Methods, 2019 - nature.com
Although messenger RNAs are key molecules for understanding life, until now, no method
has existed to determine the full-length sequence of endogenous mRNAs including their …
has existed to determine the full-length sequence of endogenous mRNAs including their …