Genetic basis of left ventricular noncompaction
P Rojanasopondist, L Nesheiwat… - Circulation: Genomic …, 2022 - Am Heart Assoc
Background: Left ventricular noncompaction (LVNC) is the third most common pediatric
cardiomyopathy characterized by a thinned myocardium and prominent trabeculations. Next …
cardiomyopathy characterized by a thinned myocardium and prominent trabeculations. Next …
Novel genetic triggers and genotype–phenotype correlations in patients with left ventricular noncompaction
K Miszalski-Jamka, JL Jefferies, W Mazur… - Circulation …, 2017 - Am Heart Assoc
Background—Left ventricular noncompaction (LVNC) is a genetically and phenotypically
heterogeneous disease and, although increasingly recognized in clinical practice, there is a …
heterogeneous disease and, although increasingly recognized in clinical practice, there is a …
Left ventricular noncompaction and congenital heart disease increases the risk of congestive heart failure
K Hirono, Y Hata, N Miyao, M Okabe… - Journal of Clinical …, 2020 - mdpi.com
Background: Left ventricular noncompaction (LVNC) is a hereditary cardiomyopathy that is
associated with high morbidity and mortality rates. Recently, LVNC was classified into …
associated with high morbidity and mortality rates. Recently, LVNC was classified into …
The importance of genetic counseling, DNA diagnostics, and cardiologic family screening in left ventricular noncompaction cardiomyopathy
YM Hoedemaekers, K Caliskan, M Michels… - Circulation …, 2010 - Am Heart Assoc
Background—Left ventricular (LV) noncompaction (LVNC) is a distinct cardiomyopathy
featuring a thickened bilayered LV wall consisting of a thick endocardial layer with …
featuring a thickened bilayered LV wall consisting of a thick endocardial layer with …
Genetic architecture of left ventricular noncompaction in adults
SB Ross, ES Singer, E Driscoll, N Nowak… - Human genome …, 2020 - nature.com
The genetic etiology and heritability of left ventricular noncompaction (LVNC) in adults is
unclear. This study sought to assess the value of genetic testing in adults with LVNC. Adults …
unclear. This study sought to assess the value of genetic testing in adults with LVNC. Adults …
Left ventricular non-compaction revisited: a distinct phenotype with genetic heterogeneity?
E Oechslin, R Jenni - European heart journal, 2011 - academic.oup.com
Non-compaction of the left ventricular myocardium (LVNC) has gained increasing
recognition during the last 25 years. There is a morphological trait of the myocardial …
recognition during the last 25 years. There is a morphological trait of the myocardial …
Genetic testing in pediatric left ventricular noncompaction
EM Miller, RB Hinton, R Czosek, A Lorts… - Circulation …, 2017 - Am Heart Assoc
Background—Left ventricular noncompaction (LVNC) can occur in isolation or can co-occur
with a cardiomyopathy phenotype or cardiovascular malformation. The yield of …
with a cardiomyopathy phenotype or cardiovascular malformation. The yield of …
Targeted panel sequencing in adult patients with left ventricular non‐compaction reveals a large genetic heterogeneity
Left ventricular non‐compaction (LVNC) is a cardiomyopathy that may be of genetic origin;
however, few data are available about the yield of mutation, the spectrum of genes and …
however, few data are available about the yield of mutation, the spectrum of genes and …
Genetic profile of left ventricular noncompaction cardiomyopathy in children—a single reference center experience
D Piekutowska-Abramczuk, A Paszkowska, E Ciara… - Genes, 2022 - mdpi.com
Background: Left ventricular noncompaction cardiomyopathy (LVNC) is a rare cardiac
disorder characterised by the presence of a two-layer myocardium with prominent …
disorder characterised by the presence of a two-layer myocardium with prominent …
Novel gene locus for autosomal dominant left ventricular noncompaction maps to chromosome 11p15
S Sasse-Klaassen, S Probst, B Gerull, E Oechslin… - Circulation, 2004 - Am Heart Assoc
Background—Left ventricular noncompaction (LVNC) is a congenital unclassified
cardiomyopathy with numerous prominent trabeculations and deep intertrabecular recesses …
cardiomyopathy with numerous prominent trabeculations and deep intertrabecular recesses …