Background: Migraine is a primary headache disorder. Despite numerous studies conducted
with the aim to understand the pathophysiology of migraine, several aspects are still unclear …

Objective This review will explore the categorization of migraine‐provoking molecules, their
cellular actions, site of action and potential drug targets based on the migraine cascade …

The understanding of migraine has moved well beyond its traditional characterization as a
“vascular headache.” In considering the basic neurobiology of migraine, it is important to …

Migraine headache carries the potential of transforming into chronic daily headache (CDH)
over a period of time. Although several risk factors for migraine progression to CDH have …

Article abstract-The trigeminal nerve transmits headache pain from blood vessels of the pia
mater and dura mater. Triggers for this pain are not well understood, but probably are …

Current theories propose that the primary dysfunction in migraine occurs within the CNS and
that this evokes changes in blood vessels within pain-producing intracranial meningeal …

Migraine is a complex disorder characterized by recurrent episodes of headache, and is one
of the most prevalent and disabling neurological disorders. A key feature of migraine is that …

Background The lower threshold of neuronal hyperexcitability has been correlated with
migraines for decades but as technology has progressed, it has now become conceivable to …

Migraine, recognized as a severe headache disorder, is widely prevalent, significantly
impacting the quality of life for those affected. This article aims to provide a comprehensive …

Migraine is one of the most prevalent and disabling neurovascular disorders worldwide.
However, despite the increase in awareness and research, the understanding of migraine …