RNA plays a quintessential role in cellular processes such as gene expression,
transcription, RNA processing, and translation. Proteins carrying out those diverse functions …

Cross-linking and mass spectrometry (XL-MS) workflows are increasingly popular
techniques for generating low-resolution structural information about interacting …

Unbiased detection of protein–protein and protein–RNA interactions within
ribonucleoprotein complexes are enabled through crosslinking followed by mass …

Cross-linking and mass spectrometry (XL-MS) workflows represent an increasingly popular
technique for low-resolution structural studies of macromolecular complexes. Cross-linking …

Protein–RNA complexes play key roles in a variety of cellular functions such as gene
expression and its regulation. One frequently applied method for the investigation of direct …

Cross-linking coupled with mass spectrometry is an increasingly popular methodology for
elucidating structural information from biological complexes. Whilst protein-protein cross …

RNA–protein interactions mediate many intracellular processes. CLIR-MS (cross-linking of
isotope-labeled RNA and tandem mass spectrometry) allows the identification of RNA …

Cross-linking mass spectrometry (XL-MS) has become a powerful strategy for defining
protein–protein interactions and elucidating architectures of large protein complexes …

Protein-RNA interactions within ribonucleoprotein particles (RNPs) can be investigated by
UV-induced crosslinking of proteins to their cognate RNAs and subsequent isolation and …

Chemical cross-linking combined with mass spectrometry (MS) is a powerful approach to
identify and map protein–protein interactions. Its applications support computational …